Evidence map›Paper›PMID 28293705›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2017

IDH mutation is paradoxically associated with higher

A Verger, Ph Metellus, Q Sala, C Colin, E Bialecki, D Taieb, O Chinot, D Figarella-Branger, E Guedj

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.

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  11. Neuro-Oncology and Radiogenomics: Time to Integrate?AJNR. American journal of neuroradiology · 2020
    Review
  12. MGMT Promoter Methylation and IDH1 Mutations Do Not Affect [International journal of molecular sciences · 2020
    Article
  13. Article
  14. Integration of dynamic parameters in the analysis ofEuropean journal of nuclear medicine and molecular imaging · 2020
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  15. Non-invasive tumor decoding and phenotyping of cerebral gliomas utilizing multiparametricEuropean journal of nuclear medicine and molecular imaging · 2020
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  16. Use of static and dynamic [EJNMMI research · 2020
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  17. Diagnostic value of PET/CT withEJNMMI research · 2020
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  20. A Nomogram ModelingFrontiers in oncology · 2020
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

A VergerDepartment of Nuclear Medicine, APHM, La Timone Hospital, Marseille, France.
Ph MetellusDepartment of Neurosurgery, Centre Hospitalier Privé Clairval, Marseille, France.
Q SalaDepartment of Nuclear Medicine, APHM, La Timone Hospital, Marseille, France.
C ColinINSERM, UMR 911, Aix-Marseille University, Marseille, France.
E BialeckiDepartment of Neurosurgery, Centre Hospitalier Privé Clairval, Marseille, France.
D TaiebDepartment of Nuclear Medicine, APHM, La Timone Hospital, Marseille, France.
O ChinotINSERM, UMR 911, Aix-Marseille University, Marseille, France.
D Figarella-BrangerINSERM, UMR 911, Aix-Marseille University, Marseille, France.
E GuedjDepartment of Nuclear Medicine, APHM, La Timone Hospital, Marseille, France. eric.guedj@ap-hm.fr.ORCID http://orcid.org/0000-0003-1912-6132
Inserm · FRAix-Marseille Université · FRCentre National de la Recherche Scientifique · FRHôpital de la Timone · FRHôpital privé Clairval · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe World Health Organization Classification of Tumors of the Central Nervous System has recently been updated by the integration of diagnostic and prognostic molecular parameters, giving pivotal attention to IDH mutation as a favourable factor. Amino acid PET is increasingly used in the management of gliomas, but its prognostic value is a matter of debate. The aim of this study was to assess the relationship between IDH mutation and

methodsA total of 43 patients, presenting with diffuse astrocytic and oligodendroglial grade II and III gliomas, reclassified according to the 2016 WHO classification of tumours of the CNS, were retrospectively included. They had all undergone

resultsPatients with IDH mutation showed higher

conclusionThis study showed paradoxically higher

Indexed as

MutationPositron-Emission TomographyAdultBiological TransportBrain NeoplasmsDihydroxyphenylalanineFemaleGliomaHumansIsocitrate DehydrogenaseMaleMiddle AgedNeoplasm GradingRetrospective StudiesDihydroxyphenylalaninefluorodopa F 18Isocitrate Dehydrogenase18F-FDOPA PETGliomasIDH mutationPrognosis

Identifiers

PMID28293705
OpenAlexW2598246083

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.