ArticlePlastic and reconstructive surgery. Global open2016
Surgical Site Infiltration for Abdominal Surgery: A Novel Neuroanatomical-based Approach.
Article in Plastic and reconstructive surgery. Global open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 39 citations in OpenAlex.
- An injectable oleogel-based bupivacaine formulation for prolonged non-opioid post-operative analgesia.Drug delivery and translational research · 2025Article
- Comparison of Analgesic Method in Laparoscopic Gastrectomy Using External Oblique Intercostal Block Versus Wound Infiltration: A Randomized Controlled Trial.Journal of clinical medicine · 2024Article
- Extended Release of Bupivacaine from Temperature-Responsive PNDJ Hydrogels Improves Postoperative Weight-Bearing in Rabbits Following Knee Surgery.Pharmaceuticals (Basel, Switzerland) · 2024Article
- Use of Muscle Relaxants for Acute Postoperative Pain: A Practical Review.Plastic and reconstructive surgery. Global open · 2024Review
- Enhanced Recovery After Surgery Pathway in Kidney Transplantation: The Road Less Traveled.Transplantation direct · 2022Article
- Article
- Basics and Best Practices of Multimodal Pain Management for the Plastic Surgeon.Plastic and reconstructive surgery. Global open · 2020Review
- Persistent Opioid Use and High-Risk Prescribing in Body Contouring Patients.Plastic and reconstructive surgery · 2019Article
- Effects of epidural analgesia on recovery after open colorectal surgery.Proceedings (Baylor University. Medical Center) · 2017Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundProvision of optimal postoperative analgesia should facilitate postoperative ambulation and rehabilitation. An optimal multimodal analgesia technique would include the use of nonopioid analgesics, including local/regional analgesic techniques such as surgical site local anesthetic infiltration. This article presents a novel approach to surgical site infiltration techniques for abdominal surgery based upon neuroanatomy.
methodsLiterature searches were conducted for studies reporting the neuroanatomical sources of pain after abdominal surgery. Also, studies identified by preceding search were reviewed for relevant publications and manually retrieved.
resultsBased on neuroanatomy, an optimal surgical site infiltration technique would consist of systematic, extensive, meticulous administration of local anesthetic into the peritoneum (or preperitoneum), subfascial, and subdermal tissue planes. The volume of local anesthetic would depend on the size of the incision such that 1 to 1.5 mL is injected every 1 to 2 cm of surgical incision per layer. It is best to infiltrate with a 22-gauge, 1.5-inch needle. The needle is inserted approximately 0.5 to 1 cm into the tissue plane, and local anesthetic solution is injected while slowly withdrawing the needle, which should reduce the risk of intravascular injection.
conclusionsMeticulous, systematic, and extensive surgical site local anesthetic infiltration in the various tissue planes including the peritoneal, musculofascial, and subdermal tissues, where pain foci originate, provides excellent postoperative pain relief. This approach should be combined with use of other nonopioid analgesics with opioids reserved for rescue. Further well-designed studies are necessary to assess the analgesic efficacy of the proposed infiltration technique.
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Registered trials
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