ArticlePlastic and reconstructive surgery. Global open2016
Comparison of Peripheral Nerve Regeneration with Side-to-side, End-to-side, and End-to-end Repairs: An Experimental Study.
Article in Plastic and reconstructive surgery. Global open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Facial nerve pathology: emerging strategies for regeneration and functional restoration.Journal of materials chemistry. B · 2025Review
- Emerging Treatments for Persistent Corneal Epithelial Defects.Vision (Basel, Switzerland) · 2025Review
- Insights on the Choice and Preparation of the Donor Nerve in Corneal Neurotization for Neurotrophic Keratopathy: A Narrative Review.Journal of clinical medicine · 2024Review
- Delayed repair of the facial nerve and its negative impacts on nerve and muscle regeneration.The journal of venomous animals and toxins including tropical diseases · 2024Article
- Morphofunctional Improvement of the Facial Nerve and Muscles with Repair Using Heterologous Fibrin Biopolymer and Photobiomodulation.Pharmaceuticals (Basel, Switzerland) · 2023Article
- Outcomes after Anterior Interosseous Nerve to Ulnar Motor Nerve Transfer.Journal of brachial plexus and peripheral nerve injury · 2023Article
- Corneal neurotization for neurotrophic keratopathy: Review of surgical techniques and outcomes.The ocular surface · 2021Review
- Protective distal side-to-side neurorrhaphy in proximal nerve injury-an experimental study with rats.Acta neurochirurgica · 2019Article
- The role of peripheral nerve surgery in a tissue reinnervation.Chinese neurosurgical journal · 2019Review
- Effect of Axonal Trauma on Nerve Regeneration in Side-to-side Neurorrhaphy: An Experimental Study.Plastic and reconstructive surgery. Global open · 2016Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe present study was conducted to find out a tool to enable improved functional recovery with proximal nerve injury. In this experimental study, nerve regeneration was compared between side-to-side (STS), end-to-side (ETS), and end-to-end repairs.
methodsThe walk track analysis was used as an outcome of functional recovery. Nerve regeneration was studied with morphometry and histology 6 or 26 weeks postoperatively.
resultsAll 3 repair techniques showed regeneration of the nerve. From 12 weeks onward, the functional results of the 3 intervention groups were significantly better compared with the unrepaired control group. End-to-end repair was significantly better when compared with the STS and ETS groups. At 26 weeks, the functional and morphometric results and histologic findings did not differ between the STS and ETS groups. The functional results correlated with the morphometric findings in all groups.
conclusionsSTS neurorrhaphy showed nerve regeneration, and the end results did not differ from clinically widely used ETS repair. Further studies are warranted to optimize the neurorrhaphy technique and examine possible applications of STS repair in peripheral nerve surgery.
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