ArticleEuropean journal of rheumatology2017
Acute digital ischemia: A rare presentation of antisynthetase syndrome.
Article in European journal of rheumatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- A case of digital vasculitis in anti-synthetase syndrome (Anti-OJ subtype).BMC rheumatology · 2025Article
- Anti-PL-12 anti-synthetase syndrome manifesting with multiple digital ischemia: Case report & review of the literature.Clinical case reports · 2024Article
- Severe finger necrosis in antisynthetase syndrome with positive anti-OJ antibodies.Clinical case reports · 2024Article
- Severe digital ischemia as an unrecognized manifestation in patients with antisynthetase autoantibodies: Case series and systematic literature review.Journal of scleroderma and related disorders · 2022Article
- Article
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Authors and funding
3 authors.
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Abstract
Antisynthetase syndrome (ASS) is recognized as a subgroup of idiopathic inflammatory myopathies (IIMs). It is associated with autoantibodies directed against aminoacyl-transfer ribonucleic acid (tRNA) synthetase enzymes. We report the first case of anti-PL-7/anti-SSA 52kD ASS presenting as acute digital ischemia, an association not described previously. Occlusive vasculopathy is a rare but serious manifestation that can be seen at presentation in patients with ASS and may herald the onset of severe interstitial lung disease (ILD). Comprehensive evaluation should be performed to confirm the presence of subclinical myositis. Extensive myositis-specific antibody testing is strongly recommended even if initial screening autoimmune serologies are unrevealing.
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