Evidence map›Paper›PMID 28293436›Full record

ArticleJournal of pregnancy2017

Placental Vitamin D-Binding Protein Expression in Human Idiopathic Fetal Growth Restriction.

Alice F Wookey, Tejasvy Chollangi, Hannah E J Yong, Bill Kalionis, Shaun P Brennecke, Padma Murthi, Harry M Georgiou

Open access · goldAbstract read
In one paragraph

Article in Journal of pregnancy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Observational
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Alice F WookeyDepartment of Maternal-Fetal Medicine, Pregnancy Research Centre, Royal Women's Hospital, Parkville, VIC 3052, Australia.
Tejasvy ChollangiDepartment of Maternal-Fetal Medicine, Pregnancy Research Centre, Royal Women's Hospital, Parkville, VIC 3052, Australia.
Hannah E J YongDepartment of Maternal-Fetal Medicine, Pregnancy Research Centre, Royal Women's Hospital, Parkville, VIC 3052, Australia.
Bill KalionisDepartment of Maternal-Fetal Medicine, Pregnancy Research Centre, Royal Women's Hospital, Parkville, VIC 3052, Australia.ORCID 0000-0002-0132-9858
Shaun P BrenneckeDepartment of Maternal-Fetal Medicine, Pregnancy Research Centre, Royal Women's Hospital, Parkville, VIC 3052, Australia; Department of Obstetrics and Gynaecology, University of Melbourne, Royal Women's Hospital, Parkville, VIC 3052, Australia.ORCID 0000-0003-3070-6971
Padma MurthiDepartment of Maternal-Fetal Medicine, Pregnancy Research Centre, Royal Women's Hospital, Parkville, VIC 3052, Australia; Department of Obstetrics and Gynaecology, University of Melbourne, Royal Women's Hospital, Parkville, VIC 3052, Australia; Department of Medicine, School of Clinical Sciences, Monash University, Clayton, VIC 3168, Australia.ORCID 0000-0003-2535-5134
Harry M GeorgiouDepartment of Obstetrics and Gynaecology, University of Melbourne, Royal Women's Hospital, Parkville, VIC 3052, Australia.ORCID 0000-0003-0553-9489
Royal Women's Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamin D-binding protein is a multifunctional serum protein with multiple actions related to normal health. Vitamin D-binding protein transports vitamin D and influences the metabolism of this key hormone but it also has additional immunomodulatory and actin-clearing properties. We investigated whether vitamin D-binding protein expression is altered in fetal growth restriction-associated placental dysfunction. Protein was extracted from 35 placentae derived from 17 healthy control subjects and 18 gestation-matched subjects with fetal growth restriction (FGR). FGR subjects were further subdivided as idiopathic (

Indexed as

AdultBiomarkersCase-Control StudiesChi-Square DistributionEnzyme-Linked Immunosorbent AssayFemaleFetal DevelopmentFetal Growth RetardationHumansPlacentaPregnancyVitamin D-Binding ProteinBiomarkersVitamin D-Binding Protein

Identifiers

PMID28293436
PMCPMC5331297
OpenAlexW2588940736

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.