Evidence map›Paper›PMID 28293281›Full record

ArticleChemistry Central journal2017

Synthesis and protective effect of new ligustrazine-vanillic acid derivatives against CoCl

Bing Xu, Xin Xu, Chenze Zhang, Yuzhong Zhang, GaoRong Wu, Mengmeng Yan, Menglu Jia, Tianxin Xie, Xiaohui Jia, Penglong Wang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Chemistry Central journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Bing XuSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 100102 China.
Xin XuSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 100102 China.
Chenze ZhangSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 100102 China.
Yuzhong ZhangDepartment of Pathology, Beijing University of Chinese Medicine, Beijing, 100102 China.
GaoRong WuSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 100102 China.
Mengmeng YanSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 100102 China.
Menglu JiaSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 100102 China.
Tianxin XieSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 100102 China.
Xiaohui JiaSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 100102 China.
Penglong WangSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 100102 China.
Haimin LeiSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 100102 China.
Beijing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ligustrazine-vanillic acid derivatives had been reported to exhibit promising neuroprotective activities. In our continuous effort to develop new ligustrazine derivatives with neuroprotective effects, we attempted the synthesis of several ligustrazine-vanillic acid amide derivatives and screened their protective effect on the injured PC12 cells damaged by CoCl

Indexed as

Neuroprotective effectPC12 cellSynthesisT-VA amide derivatives

Identifiers

PMID28293281
PMCPMC5331027
OpenAlexW2594334080

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.