Evidence map›Paper›PMID 28293190›Full record

ArticleFrontiers in pharmacology2017

GABA, Selank, and Olanzapine Affect the Expression of Genes Involved in GABAergic Neurotransmission in IMR-32 Cells.

Elena Filatova, Anastasiya Kasian, Timur Kolomin, Ekaterina Rybalkina, Anelya Alieva, Lyudmila Andreeva, Svetlana Limborska, Nikolay Myasoedov, Galina Pavlova, Petr Slominsky and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Elena FilatovaDepartment of Molecular Basis of Human Genetics, Institute of Molecular Genetics, Russian Academy of Sciences Moscow, Russia.
Anastasiya KasianDepartment of Molecular Basis of Human Genetics, Institute of Molecular Genetics, Russian Academy of Sciences Moscow, Russia.
Timur KolominDepartment of Molecular Basis of Human Genetics, Institute of Molecular Genetics, Russian Academy of Sciences Moscow, Russia.
Ekaterina RybalkinaLaboratory of Tumor Cells Genetics, Blokhin Russian Cancer Research Center, Ministry of Health of the Russian Federation Moscow, Russia.
Anelya AlievaDepartment of Molecular Basis of Human Genetics, Institute of Molecular Genetics, Russian Academy of Sciences Moscow, Russia.
Lyudmila AndreevaDepartment of Chemistry of Physiologically Active Compounds, Institute of Molecular Genetics, Russian Academy of Sciences Moscow, Russia.
Svetlana LimborskaDepartment of Molecular Basis of Human Genetics, Institute of Molecular Genetics, Russian Academy of Sciences Moscow, Russia.
Nikolay MyasoedovDepartment of Chemistry of Physiologically Active Compounds, Institute of Molecular Genetics, Russian Academy of Sciences Moscow, Russia.
Galina PavlovaGroup of Neurogenetics and Developmental Genetics, Institute of Gene Biology, Russian Academy of Sciences Moscow, Russia.
Petr SlominskyDepartment of Molecular Basis of Human Genetics, Institute of Molecular Genetics, Russian Academy of Sciences Moscow, Russia.
Maria ShadrinaDepartment of Molecular Basis of Human Genetics, Institute of Molecular Genetics, Russian Academy of Sciences Moscow, Russia.
Institute of Molecular Genetics · RUInstitute of Gene Biology · RUMinistry of Health of the Russian Federation · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinical studies have shown that Selank had an anxiolytic effect comparable to that of classical benzodiazepine drugs, which can enhance the inhibitory effect of GABA by allosteric modulation of GABA

Indexed as

GABAgene expressionIMR-32 cellsolanzapineSelank

Identifiers

PMID28293190
PMCPMC5328971
OpenAlexW2593886805

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.