Evidence map›Paper›PMID 28293095›Full record

ArticleWorld journal of gastroenterology2017

Different phenotypes of monocytes in patients with new-onset mild acute pancreatitis.

Man-Li Zhang, Yan-Fang Jiang, Xin-Rui Wang, Li-Li Ding, Hong-Juan Wang, Qing-Qing Meng, Pu-Jun Gao

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Circulating monocytes in acute pancreatitis.Frontiers in immunology · 2022
    Review
  6. Article
  7. Article
  8. Chronic Pancreatitis and the Development of Pancreatic Cancer.Endocrine, metabolic & immune disorders drug targets · 2020
    Review
  9. Observational
  10. Article
  11. Circulating CD14Mediators of inflammation · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Man-Li ZhangMan-Li Zhang, Qing-Qing Meng, Department of Hepatology and Gastroenterology, The Second Part of First Hospital of Jilin University, Changchun 130021, Jilin Province, China.
Yan-Fang JiangMan-Li Zhang, Qing-Qing Meng, Department of Hepatology and Gastroenterology, The Second Part of First Hospital of Jilin University, Changchun 130021, Jilin Province, China.
Xin-Rui WangMan-Li Zhang, Qing-Qing Meng, Department of Hepatology and Gastroenterology, The Second Part of First Hospital of Jilin University, Changchun 130021, Jilin Province, China.
Li-Li DingMan-Li Zhang, Qing-Qing Meng, Department of Hepatology and Gastroenterology, The Second Part of First Hospital of Jilin University, Changchun 130021, Jilin Province, China.
Hong-Juan WangMan-Li Zhang, Qing-Qing Meng, Department of Hepatology and Gastroenterology, The Second Part of First Hospital of Jilin University, Changchun 130021, Jilin Province, China.
Qing-Qing MengMan-Li Zhang, Qing-Qing Meng, Department of Hepatology and Gastroenterology, The Second Part of First Hospital of Jilin University, Changchun 130021, Jilin Province, China.
Pu-Jun GaoMan-Li Zhang, Qing-Qing Meng, Department of Hepatology and Gastroenterology, The Second Part of First Hospital of Jilin University, Changchun 130021, Jilin Province, China.
First Hospital of Jilin University · CNJilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the numbers of different subsets of monocytes and their associations with the values of clinical measures in mild acute pancreatitis (MAP) patients.

methodsThe study included one group of 13 healthy controls and another group of 24 patients with new-onset MAP. The numbers of different subsets of monocytes were examined in these two groups of subjects by flow cytometry. The concentrations of plasma interleukin (IL)-10 and IL-12 were determined by cytometric bead array. The acute physiology and chronic health evaluation (APACHE) II scores of individual patients were evaluated, and the levels of plasma C-reactive protein (CRP) as well as the activities of amylase and lipase were measured.

resultsIn comparison with that in the controls, significantly increased numbers of CD14+CD163-, CD14+CD163-MAC387+ M1 monocytes, but significantly reduced numbers of CD14+CD163+IL-10+ M2 monocytes were detected in the MAP patients (

conclusionIncreased numbers of CD14+CD163- and CD14+ CD163-MAC387+ monocytes may contribute to the pathogenesis of MAP, and increased numbers of CD14+CD163+CD115+ monocytes may be a biomarker for evaluating the severity of MAP.

Indexed as

Acute DiseaseAdultAmylasesAntigens, CDAntigens, Differentiation, MyelomonocyticCase-Control StudiesCD163 AntigenC-Reactive ProteinCytokinesFemaleHumansInflammationInterleukin-10Interleukin-12LipaseLipopolysaccharide ReceptorsAmylasesAntigens, CDAntigens, Differentiation, MyelomonocyticCD163 AntigenC-Reactive ProteinCytokinesIL10 protein, humanInterleukin-10Interleukin-12LipaseLipopolysaccharide ReceptorsReceptor, Macrophage Colony-Stimulating FactorReceptors, Cell SurfaceAcute physiology and chronic health evaluation II scoreC-reactive proteinCytokineMild acute pancreatitisMonocyte

Identifiers

PMID28293095
PMCPMC5330833
OpenAlexW2590621034

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.