Evidence map›Paper›PMID 28292986›Full record

ArticlemBio2017

Arginine Is a Critical Substrate for the Pathogenesis of

Jake Everett, Keith Turner, Qiuxian Cai, Vernita Gordon, Marvin Whiteley, Kendra Rumbaugh

Open access · goldAbstract read
In one paragraph

Article in mBio, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 43 citations in OpenAlex.

  1. An extragenic fix for a broken enzyme.Microbiology (Reading, England) · 2026
    Article
  2. Altered distribution of chronicity-deficientMicrobiology (Reading, England) · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Arginine at the host-pathogen interface.Infection and immunity · 2025
    Review
  7. Frontiers in medicine · 2025
    Article
  8. Effect of L-arginine on cystic fibrosisAntimicrobial agents and chemotherapy · 2024
    Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Nutrient Sensing and Biofilm Modulation: The Example of L-arginine inInternational journal of molecular sciences · 2022
    Review
  15. Sub-Inhibitory Antibiotic Exposure and Virulence inAntibiotics (Basel, Switzerland) · 2021
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jake EverettDepartment of Surgery, Texas Tech University Health Sciences Center, Lubbock, Texas, USA.
Keith TurnerDepartment of Molecular Biosciences, Institute of Cellular and Molecular Biology, John Ring LaMontagne Center for Infectious Disease, The University of Texas at Austin, Austin, Texas, USA.
Qiuxian CaiDepartment of Physics, the University of Texas at Austin, Austin, Texas, USA.
Vernita GordonDepartment of Physics, the University of Texas at Austin, Austin, Texas, USA.
Marvin WhiteleyDepartment of Molecular Biosciences, Institute of Cellular and Molecular Biology, John Ring LaMontagne Center for Infectious Disease, The University of Texas at Austin, Austin, Texas, USA.
Kendra RumbaughDepartment of Surgery, Texas Tech University Health Sciences Center, Lubbock, Texas, USA kendra.rumbaugh@ttuhsc.edu.
The University of Texas at Austin · USTexas Tech University Health Sciences Center · US

Funding

Mechanisms of Pseudomonas aeruginosa virulence in polymicrobial wound infectionsR01GM116547 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI WHITELEY, MARVIN · 2016 to 2019
$1.2M
Pseudomonas aeruginosa and Staphylococcus aureus Interspecies Interactions in WouR15AI105763 · NIAID · TEXAS TECH UNIVERSITY HEALTH SCIS CENTER · PI RUMBAUGH, KENDRA P · 2014 to 2014
$448k
NIAID NIH HHS R15 AI105763NIGMS NIH HHS R01 GM116547
6 · The paper itself

Abstract

Environmental conditions affect bacterial behavior and can greatly influence the course of an infection. However, the environmental cues that elicit bacterial responses in specific infection sites are relatively unknown.

Indexed as

AnimalsAnti-Bacterial AgentsArginineBurnsDisease Models, AnimalMicePseudomonas aeruginosaPseudomonas InfectionsSurvival AnalysisTreatment OutcomeVirulenceWound InfectionAnti-Bacterial AgentsArginine

Identifiers

PMID28292986
PMCPMC5350470
OpenAlexW2595134130

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.