Evidence map›Paper›PMID 28292915›Full record

ReviewMolecular biology of the cell2017

A cascade of multiple proteins and lipids catalyzes membrane fusion.

William Wickner, Josep Rizo

Abstract readReview
In one paragraph

Review in Molecular biology of the cell, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. A lever hypothesis for Synaptotagmin-1 action in neurotransmitter release.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Mechanisms of SNARE proteins in membrane fusion.Nature reviews. Molecular cell biology · 2024
    Review
  12. The role ofFrontiers in microbiology · 2024
    Review
  13. Article
  14. The machinery of vesicle fusion.Current opinion in cell biology · 2023
    Review
  15. Article
  16. Article
  17. Review
  18. Lipid and Lipidation in Membrane Fusion.The Journal of membrane biology · 2022
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

William WicknerDepartment of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth, Hanover, NH 03755 Bill.Wickner@Dartmouth.edu) Jose.Rizo-Rey@UTSouthwestern.edu.
Josep RizoDepartments of Biophysics, Biochemistry, and Biophysics, University of Texas Southwestern Medical Center, Dallas, TX 75390 Bill.Wickner@Dartmouth.edu) Jose.Rizo-Rey@UTSouthwestern.edu.

Funding

Mechanisms of Membrane FusionR35GM118037 · NIGMS · DARTMOUTH COLLEGE · PI WILLIAM Tobey WICKNER · 2016 to 2026
$8.6M
Mechanisms of neurotransmitter release and its regulationR35NS097333 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI RIZOREY, JOSE · 2017 to 2024
$7.0M
NIGMS NIH HHS R35 GM118037NINDS NIH HHS R35 NS097333
6 · The paper itself

Abstract

Recent studies suggest revisions to the SNARE paradigm of membrane fusion. Membrane tethers and/or SNAREs recruit proteins of the Sec 1/Munc18 family to catalyze SNARE assembly into

Indexed as

AnimalsHumansLipidsMembrane FusionMembrane ProteinsMunc18 ProteinsProtein BindingSNARE ProteinsSoluble N-Ethylmaleimide-Sensitive Factor Attachment ProteinsLipidsMembrane ProteinsMunc18 ProteinsSNARE ProteinsSoluble N-Ethylmaleimide-Sensitive Factor Attachment Proteins

Identifiers

PMID28292915
PMCPMC5349777

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.