Evidence map›Paper›PMID 28292888›Full record

ArticlePhysiological reports2017

Antibody-mediated inhibition of EGFR reduces phosphate excretion and induces hyperphosphatemia and mild hypomagnesemia in mice.

Bernardo Ortega, Jason M Dey, Allison R Gardella, Jacob Proano, Deanna Vaneerde

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physiological reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Bernardo OrtegaDepartment of Biology, The College at Brockport State University of New York, Brockport, New York bortega@brockport.edu.ORCID http://orcid.org/0000-0002-3473-7778
Jason M DeyDepartment of Biology, The College at Brockport State University of New York, Brockport, New York.
Allison R GardellaDepartment of Biology, The College at Brockport State University of New York, Brockport, New York.
Jacob ProanoDepartment of Biology, The College at Brockport State University of New York, Brockport, New York.
Deanna VaneerdeDepartment of Biology, The College at Brockport State University of New York, Brockport, New York.
SUNY Brockport · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monoclonal antibody therapies targeting the EGF receptor (EGFR) frequently result in hypomagnesemia in human patients. In contrast, EGFR tyrosine kinase inhibitors do not affect Mg

Indexed as

Antibodies, MonoclonalAnimalsErbB ReceptorsFibroblast Growth Factor-23HypercalciuriaHyperphosphatemiaIon TransportKidney Tubules, DistalMagnesiumMiceNephrocalcinosisPhosphatesRenal Tubular Transport, Inborn ErrorsAntibodies, MonoclonalEGFR protein, mouseErbB ReceptorsFGF23 protein, humanFgf23 protein, mouseFibroblast Growth Factor-23MagnesiumPhosphatesEGFRFGF23Klothomagnesium deficiencyphosphatePTH

Identifiers

PMID28292888
PMCPMC5350180
OpenAlexW2603862034

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.