Evidence map›Paper›PMID 28292887›Full record

ArticlePhysiological reports2017

Orai and TRPC channel characterization in Fc

Hannah E Wajdner, Jasmine Farrington, Claire Barnard, Peter T Peachell, Christine G Schnackenberg, Joseph P Marino, Xiaoping Xu, Karen Affleck, Malcolm Begg, Elizabeth P Seward

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.8field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Reduction of TRPC1/TRPC3 mediated CaCellular signalling · 2023
    Article
  7. Article
  8. Article
  9. TRPA1 Expression and Pathophysiology in Immune Cells.International journal of molecular sciences · 2021
    Review
  10. Article
  11. Review
  12. A Critical Role for NaJournal of immunology (Baltimore, Md. : 1950) · 2021
    Article
  13. Article
  14. Deciphering the Role of Endolysosomal CaFrontiers in immunology · 2021
    Review
  15. Article
  16. Analysis of Mrgprb2 Receptor-Evoked CaFrontiers in immunology · 2020
    Article
  17. Article
  18. Review
  19. Channels (Austin, Tex.) · 2019
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Hannah E WajdnerDepartment of Biomedical Science, University of Sheffield Western Bank, Sheffield, UK.
Jasmine FarringtonDepartment of Biomedical Science, University of Sheffield Western Bank, Sheffield, UK.
Claire BarnardDepartment of Biomedical Science, University of Sheffield Western Bank, Sheffield, UK.
Peter T PeachellAcademic Unit of Respiratory Medicine, University of Sheffield The Royal Hallamshire Hospital, Sheffield, UK.
Christine G SchnackenbergMetabolic Pathways and Cardiovascular Unit, GlaxoSmithKline, King of Prussia, Pennsylvania.
Joseph P MarinoMetabolic Pathways and Cardiovascular Unit, GlaxoSmithKline, King of Prussia, Pennsylvania.
Xiaoping XuMetabolic Pathways and Cardiovascular Unit, GlaxoSmithKline, King of Prussia, Pennsylvania.
Karen AffleckRespiratory Therapy Area Unit, GlaxoSmithKline, Stevenage, UK.
Malcolm BeggRespiratory Therapy Area Unit, GlaxoSmithKline, Stevenage, UK.
Elizabeth P SewardDepartment of Biomedical Science, University of Sheffield Western Bank, Sheffield, UK e.p.seward@sheffield.ac.uk.ORCID http://orcid.org/0000-0001-5311-1343
University of Sheffield · GBPathways Behavioral Services · USGlaxoSmithKline (United Kingdom) · GBRoyal Hallamshire Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inappropriate activation of mast cells via the Fc

Indexed as

CalciumCalcium Release Activated Calcium ChannelsCalcium SignalingCell LineHumansLungMast CellsReceptors, IgETRPC Cation ChannelsCalciumCalcium Release Activated Calcium ChannelsReceptors, IgETRPC Cation ChannelsCalciumcytokineFcεRIhumanmast cellOraiSTIMTRPC

Identifiers

PMID28292887
PMCPMC5350174
OpenAlexW2596617873

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.