Evidence map›Paper›PMID 28292847›Full record

ArticleDevelopment (Cambridge, England)2017

Human umbilical cord blood-borne fibroblasts contain marrow niche precursors that form a bone/marrow organoid

Alice Pievani, Benedetto Sacchetti, Alessandro Corsi, Benedetta Rambaldi, Samantha Donsante, Valeria Scagliotti, Patrizia Vergani, Cristina Remoli, Andrea Biondi, Pamela G Robey and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Development (Cambridge, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 31 citations in OpenAlex.

  1. Organoids for disease modeling and treatment: state-of-the-art.Experimental hematology & oncology · 2026
    Review
  2. 3DACS biomaterials science & engineering · 2026
    Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. AnFrontiers in cellular and infection microbiology · 2023
    Article
  12. Bone Marrow Niches of Hematopoietic Stem and Progenitor Cells.International journal of molecular sciences · 2022
    Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Alice PievaniDulbecco Telethon Institute, Tettamanti Research Center, Pediatric Department, University of Milano-Bicocca, Monza 20900, Italy.
Benedetto SacchettiDepartment of Molecular Medicine, Sapienza University of Rome, Rome 00161, Italy.
Alessandro CorsiDepartment of Molecular Medicine, Sapienza University of Rome, Rome 00161, Italy.
Benedetta RambaldiPediatric Department, University of Milano-Bicocca, San Gerardo Hospital/Fondazione MBBM, Monza 20900, Italy.
Samantha DonsanteDepartment of Molecular Medicine, Sapienza University of Rome, Rome 00161, Italy.
Valeria ScagliottiDulbecco Telethon Institute, Tettamanti Research Center, Pediatric Department, University of Milano-Bicocca, Monza 20900, Italy.
Patrizia VerganiDepartment of Obstetrics and Gynecology, University of Milano-Bicocca, Monza 20900, Italy.
Cristina RemoliDepartment of Molecular Medicine, Sapienza University of Rome, Rome 00161, Italy.
Andrea BiondiPediatric Department, University of Milano-Bicocca, San Gerardo Hospital/Fondazione MBBM, Monza 20900, Italy.
Pamela G RobeySkeletal Biology Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA.
Mara RiminucciDepartment of Molecular Medicine, Sapienza University of Rome, Rome 00161, Italy serafinim72@gmail.com mara.riminucci@uniroma1.it.ORCID 0000-0002-8643-9211
Marta SerafiniDulbecco Telethon Institute, Tettamanti Research Center, Pediatric Department, University of Milano-Bicocca, Monza 20900, Italy serafinim72@gmail.com mara.riminucci@uniroma1.it.ORCID 0000-0001-8105-6476
Sapienza University of Rome · ITDulbecco Telethon Institute · ITUniversity of Milano-Bicocca · ITNational Institutes of Health · US

Funding

The role of stem cells in skeletal health and diseaseZIADE000380 · NIDCR · NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH · PI ROBEY, PAMELA G · 2009 to 2025
$30.6M
Intramural NIH HHS ZIA DE000380
6 · The paper itself

Abstract

Human umbilical cord blood (CB) has attracted much attention as a reservoir for functional hematopoietic stem and progenitor cells, and, recently, as a source of blood-borne fibroblasts (CB-BFs). Previously, we demonstrated that bone marrow stromal cell (BMSC) and CB-BF pellet cultures make cartilage

Indexed as

Stem Cell NicheAdultBone Marrow CellsCell CompartmentationChildFetal BloodFibroblastsHematopoietic Stem CellsHematopoietic Stem Cell TransplantationHomeostasisHumansOrganoidsStromal CellsBone marrow organoidCord blood-borne fibroblastsHematopoietic stem cell nicheUmbilical cord blood

Identifiers

PMID28292847
PMCPMC5358110
OpenAlexW2599489450

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.