ArticleBMJ (Clinical research ed.)2017
Association between concurrent use of prescription opioids and benzodiazepines and overdose: retrospective analysis.
Article in BMJ (Clinical research ed.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03675386 (Ontario Transitional Pain and Opioid Safety Program), which is not on this map. Cited by 285 papers, 11 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Ontario Transitional Pain and Opioid Safety Program: Improving Pain and Opioid Practices for Complex Chronic Pain Patients Following Surgery
Who cites it
285 citing papers in PubMed, 11 syntheses or guidelines pooled it, 514 citations in OpenAlex.
- Patient-related risk factors for new persistent opioid use after surgery among opioid-naïve individuals in the United States: a systematic review and meta-analysis.Pain medicine (Malden, Mass.) · 2026Pooled it
- Joint Clinical Practice Guideline on Benzodiazepine Tapering: Considerations When Risks Outweigh Benefits.Journal of general internal medicine · 2025Guideline
- Use of sensitivity analyses to assess uncontrolled confounding from unmeasured variables in observational, active comparator pharmacoepidemiologic studies: a systematic review.American journal of epidemiology · 2025Pooled it
- The association between benzodiazepine co-prescription, opioid agonist treatment and mortality: a systematic review.BMC psychiatry · 2024Pooled it
- Incidence and risk factors of new persistent opioid use after surgery and trauma: A systematic review.BMC surgery · 2024Pooled it
- Predictors of fatal and nonfatal overdose after prescription of opioids for chronic pain: a systematic review and meta-analysis of observational studies.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023Pooled it
- CDC Clinical Practice Guideline for Prescribing Opioids for Pain - United States, 2022.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2022Guideline
- Application of a diazepam milligram equivalency algorithm to assess benzodiazepine dose intensity in Rhode Island in 2018.Journal of managed care & specialty pharmacy · 2022Pooled it
- CDC Guideline For Opioid Prescribing Associated With Reduced Dispensing To Certain Patients With Chronic Pain.Health affairs (Project Hope) · 2021Guideline
- [Recommendations of the second update of the LONTS guidelines : Long-term opioid therapy for chronic noncancer pain].Schmerz (Berlin, Germany) · 2020Pooled it
- Factors associated with the prescribing of high-dose opioids in primary care: a systematic review and meta-analysis.BMC medicine · 2020Pooled it
- Effect of Paroxetine or Escitalopram Coadministered with Oxycodone versus Oxycodone Alone on Ventilation during Hypercapnia: A Randomized Clinical Trial.Anesthesiology · 2026Trial
- Multimethod analysis of adherence to preventive treatment for tuberculosis: a pragmatic randomized clinical trial.BMC infectious diseases · 2026Trial
- Electronic Intervention for Patient-Managed Benzodiazepine Tapering: A Randomized Clinical Trial.JAMA network open · 2026Trial
- Effect of midazolam co-administered with oxycodone on ventilation: a randomised clinical trial in healthy volunteers.British journal of anaesthesia · 2025Trial
- Trial
- Effect of Pharmacist Email Alerts on Concurrent Prescribing of Opioids and Benzodiazepines by Prescribers and Primary Care Managers: A Randomized Clinical Trial.JAMA health forum · 2022Trial
- Reducing prescribing of benzodiazepines in older adults: a comparison of four physician-focused interventions by a medical regulatory authority.BMC family practice · 2021Trial
- Randomized Crossover Trial to Compare Abuse Liability of Intravenous Remimazolam Versus Intravenous Midazolam and Placebo in Recreational Central Nervous System Depressant Users.Journal of clinical pharmacology · 2020Trial
- Changes in opioid prescribing and high-risk co-prescribing after implementation of the 2016 CDC opioid guideline among older adults with and without cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
225 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.