Evidence map›Paper›PMID 28292763›Full record

ArticleAmerican journal of physiology. Endocrinology and metabolism2017

Oxygen delivery and the restoration of the muscle energetic balance following exercise: implications for delayed muscle recovery in patients with COPD.

Gwenael Layec, Corey R Hart, Joel D Trinity, Oh-Sung Kwon, Matthew J Rossman, Ryan M Broxterman, Yann Le Fur, Eun-Kee Jeong, Russell S Richardson

Open access · greenAbstract readControlled Clinical Trial
In one paragraph

Article in American journal of physiology. Endocrinology and metabolism, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. NMR in biomedicine · 2025
    Pooled it
  2. Acute Effect of Inspiratory Muscle Training on Peripheral Tissue Oxygenation Behavior in Individuals With COPD: A Randomized Crossover Study.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026
    Trial
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Frontiers in physiology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Gwenael LayecDepartment of Medicine, Division of Geriatrics, University of Utah, Salt Lake City, Utah; gwenael.layec@utah.edu.
Corey R HartGeriatric Research, Education, and Clinical Center, George E. Whalen Veterans Affairs Medical Center, Salt Lake City, Utah.
Joel D TrinityDepartment of Medicine, Division of Geriatrics, University of Utah, Salt Lake City, Utah.
Oh-Sung KwonDepartment of Medicine, Division of Geriatrics, University of Utah, Salt Lake City, Utah.
Matthew J RossmanGeriatric Research, Education, and Clinical Center, George E. Whalen Veterans Affairs Medical Center, Salt Lake City, Utah.
Ryan M BroxtermanDepartment of Medicine, Division of Geriatrics, University of Utah, Salt Lake City, Utah.
Yann Le FurCentre de Résonance Magnétique Biologique et Médicale, Aix-Marseille Universite, Centre National de la Recherche Scientifique, Marseille, France; and.
Eun-Kee JeongDepartment of Radiology and Utah Center for Advanced Imaging Research, University of Utah, Salt Lake City, Utah.
Russell S RichardsonDepartment of Medicine, Division of Geriatrics, University of Utah, Salt Lake City, Utah.
University of Utah · USGeriatric Research Education and Clinical Center · USAdvanced Imaging Research (United States) · USCentre de Résonance Magnétique Biologique et Médicale · FR

Funding

Tissue Imaging, Biochemistry and MorphologyP01HL091830 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WAGNER, PETER D · 2009 to 2013
$10.1M
Nitric oxide coupling and BH4 availability roles in muscle dysfunction with COPDK99HL125756 · NHLBI · UNIVERSITY OF UTAH · PI LAYEC, GWENAEL · 2015 to 2016
$300k
Understanding the Exercise-Hypertension Paradox: Implication for RehabilitationIK2RX001215 · VA · VA SALT LAKE CITY HEALTHCARE SYSTEM · PI TRINITY, JOEL DOUGLAS · 2014 to 2018
–
NHLBI NIH HHS K99 HL125756NHLBI NIH HHS P01 HL091830RRD VA IK2 RX001215
6 · The paper itself

Abstract

Patients with chronic obstructive pulmonary disease (COPD) experience a delayed recovery from skeletal muscle fatigue following exhaustive exercise that likely contributes to their progressive loss of mobility. As this phenomenon is not well understood, this study sought to examine postexercise peripheral oxygen (O

Indexed as

ExerciseExercise ToleranceOxygen ConsumptionAgedEnergy MetabolismExercise TherapyFemaleHumansMaleMuscle FatigueMuscle, SkeletalMuscle StrengthPulmonary Disease, Chronic ObstructiveRecovery of Function31P-MRSCOPDmitochondrial functionmuscle fatigueO2 availabilityPCr recovery kinetics

Identifiers

PMID28292763
PMCPMC6109703
OpenAlexW2596723702

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.