Evidence map›Paper›PMID 28292639›Full record

ReviewTrends in cognitive sciences2017

Oculomotor Prediction: A Window into the Psychotic Mind.

Katharine N Thakkar, Vaibhav A Diwadkar, Martin Rolfs

Abstract readReview
In one paragraph

Review in Trends in cognitive sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
10.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 65 citations in OpenAlex.

  1. Article
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  3. Review
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  14. Reconciling competing mechanisms posited to underlie auditory verbal hallucinations.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021
    Article
  15. Article
  16. Article
  17. Organization of Corollary Discharge Neurons in Monkey Medial Dorsal Thalamus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
  18. Article
  19. Article
  20. Disrupted Corollary Discharge in Schizophrenia: Evidence From the Oculomotor System.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Katharine N ThakkarDepartment of Psychology, Michigan State University, East Lansing, MI, USA. Electronic address: kthakkar@msu.edu.
Vaibhav A DiwadkarDepartment of Psychiatry and Behavioral Neurosciences, Brain Imaging Research Division, Wayne State University, Detroit, MI, USA.
Martin RolfsBernstein Center for Computational Neuroscience and Department of Psychology, Humboldt Universität, 10099 Berlin, Germany.
Bernstein Center for Computational Neuroscience Berlin · DEMichigan State University · USWayne State University · US

Funding

Multimodal Investigation of Excitatory/Inhibitory Imbalances and Network Dysfunction Related to Motor Control in OCD Youth: ¹H fMRS and fMRI ApplicationsR01MH059299 · NIMH · WAYNE STATE UNIVERSITY · PI DIWADKAR, VAIBHAV A., ROSENBERG, DAVID R · 1999 to 2025
$11.1M
Advancing innovative brain imaging to detect altered glutamate modulation and network dynamics in schizophreniaR01MH111177 · NIMH · WAYNE STATE UNIVERSITY · PI DIWADKAR, VAIBHAV A., STANLEY, JEFFREY A · 2016 to 2020
$2.9M
NIMH NIH HHS R01 MH059299NIMH NIH HHS R01 MH111177
6 · The paper itself

Abstract

Psychosis - an impaired contact with reality - is a hallmark of schizophrenia. Many psychotic symptoms are associated with disruptions in agency - the sense that 'I' cause my actions. A failure to predict sensory consequences of one's own actions may underlie agency disturbances. Such predictions rely on corollary discharge (CD) signals, 'copies' of movement commands sent to sensory regions prior to action execution. Here, we make a case that the oculomotor system is a promising model for understanding CD in psychosis, building on advances in our understanding of the behavioral and neurophysiological correlates of CD associated with eye movements. In this opinion article, we provide an overview of recent evidence for disturbed oculomotor CD in schizophrenia, potentially linking bizarre and disturbing psychotic experiences with basic physiological processes.

Indexed as

Eye MovementsPsychotic DisordersHumansMovementSchizophreniaSensation

Identifiers

PMID28292639
PMCPMC5401650
OpenAlexW2593348554

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.