ArticleFertility and sterility2017
Perinatal outcomes among singletons after assisted reproductive technology with single-embryo or double-embryo transfer versus no assisted reproductive technology.
Article in Fertility and sterility, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 53 citations in OpenAlex.
- Vasodilators for women undergoing fertility treatment.The Cochrane database of systematic reviews · 2025Pooled it
- Vasodilators for women undergoing fertility treatment.The Cochrane database of systematic reviews · 2018Pooled it
- Correlation of low birth weight with infertility and ART treatment: single-center cohort analysis of 7697 singleton live births.BMC pregnancy and childbirth · 2026Article
- Effects of prolonged embryo cryopreservation after fertility treatment in Denmark.Reproduction & fertility · 2026Article
- Maternal, pregnancy, and neonatal outcomes associated with surrogacy: a scoping review.Reproductive biology and endocrinology : RB&E · 2026Review
- Introducing the Blastocyst Fragmentation Indicator (BFI): A Novel Time-Lapse Metric for Enhanced Aneuploidy Risk Stratification in Non-Invasive Embryo Assessment.JBRA assisted reproduction · 2026Article
- Comparison of obstetric outcomes between single and double embryo transfers among singleton live births from vitrified donor oocyte IVF cycles: a cohort study.Journal of gynecology obstetrics and human reproduction · 2025Article
- The transfer of double morphologically good Day 5 blastocysts increases the risk of clinical pregnancy loss in singleton pregnancies following frozen-thawed embryo transfer.Frontiers in endocrinology · 2025Article
- Metabolic Status and Expression Level of SREBP mRNA and Mir-33 Among Children Conceived by Assisted Reproductive Technology.International journal of genomics · 2025Article
- The association between type of conception through medically assisted reproduction and childhood cognition: a Danish population-wide cohort study.European journal of public health · 2023Article
- Assisted Reproductive Technology and Perinatal Mortality: Selected States (2006-2011).American journal of perinatology · 2023Article
- Article
- Conception by fertility treatment and cardiometabolic risk in middle childhood.Fertility and sterility · 2022Article
- Assisted Reproductive Technology Surveillance - United States, 2018.Morbidity and mortality weekly report. Surveillance summaries (Washington, D.C. : 2002) · 2022Article
- Association of Preterm Singleton Birth With Fertility Treatment in the US.JAMA network open · 2022Article
- Pregnancy and Perinatal Outcomes of Patients With Prior Cesarean Section After a Single Embryo Transfer in IVF/ICSI: A Retrospective Cohort Study.Frontiers in endocrinology · 2022Article
- Comparison of Clinical Pregnancy Outcomes after Fresh and Frozen Embryo Transfer.Computational and mathematical methods in medicine · 2022Article
- The cognitive development from childhood to adolescence of low birthweight children born after medically assisted reproduction-a UK longitudinal cohort study.International journal of epidemiology · 2021Article
- Clinical outcomes after single-versus double-embryo transfers in women with adenomyosis: a retrospective study.Archives of gynecology and obstetrics · 2021Article
- Reduction in multiple pregnancy rate in donor oocyte-recipient gestational carrier (GC) in vitro fertilization (IVF) cycles in the USA with single-embryo transfer and preimplantation genetic testing.Journal of assisted reproduction and genetics · 2021Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 1 country.
Funding
Abstract
objectiveTo examine outcomes of singleton pregnancies conceived without assisted reproductive technology (non-ART) compared with singletons conceived with ART by elective single-embryo transfer (eSET), nonelective single-embryo transfer (non-eSET), and double-embryo transfer with the establishment of 1 (DET -1) or ≥2 (DET ≥2) early fetal heartbeats.
designRetrospective cohort using linked ART surveillance data and vital records from Florida, Massachusetts, Michigan, and Connecticut.
settingNot applicable. PATIENT(S): Singleton live-born infants. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Preterm birth (PTB <37 weeks), very preterm birth (VPTB <32 weeks), small for gestational age birth weight (<10th percentile), low birth weight (LBW <2,500 g), very low birth weight (VLBW <1,500 g), 5-minute Apgar score <7, and neonatal intensive care unit (NICU) admission. RESULT(S): After controlling for maternal characteristics and employing a weighted propensity score approach, we found that singletons conceived after eSET were less likely to have a 5-minute Apgar <7 (adjusted odds ratio [aOR] 0.33; 95% CI, 0.15-0.69) compared with non-ART singletons. There were no differences among outcomes between non-ART and non-eSET infants. We found that PTB, VPTB, LBW, and VLBW were more likely among DET -1 and DET ≥2 compared with non-ART infants, with the odds being higher for DET ≥2 (PTB aOR 1.58; 95% CI, 1.09-2.29; VPTB aOR 2.46; 95% CI, 1.20-5.04; LBW aOR 2.17; 95% CI, 1.24-3.79; VLBW aOR 3.67; 95% CI, 1.38-9.77). CONCLUSION(S): Compared with non-ART singletons, singletons born after eSET and non-eSET did not have increased risks whereas DET -1 and DET ≥2 singletons were more likely to have adverse perinatal outcomes.
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Registered trials
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