Evidence map›Paper›PMID 28292306›Full record

ArticleReproductive health2017

Fertility and HIV following universal access to ART in Rwanda: a cross-sectional analysis of Demographic and Health Survey data.

Eric Remera, Kimberly Boer, Stella M Umuhoza, Bethany L Hedt-Gauthier, Dana R Thomson, Patrick Ndimubanzi, Eugenie Kayirangwa, Salomon Mutsinzi, Alice Bayingana, Placidie Mugwaneza and 1 more

Open access · goldAbstract read
In one paragraph

Article in Reproductive health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
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  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Eric RemeraInstitute of HIV/AIDS Disease Prevention and Control, Rwanda Biomedical Center, Kigali, Rwanda. ericremera@gmail.com.ORCID http://orcid.org/0000-0002-6084-8877
Kimberly BoerCenters for Disease Control and Prevention, Kigali, Rwanda.
Stella M UmuhozaCollege of Medicine and Health Sciences, School of Public Health, University of Rwanda, Kigali, Rwanda.
Bethany L Hedt-GauthierCollege of Medicine and Health Sciences, School of Public Health, University of Rwanda, Kigali, Rwanda.
Dana R ThomsonDepartment of Global Health and Social Medicine, Harvard Medical School, Boston, USA.
Patrick NdimubanziCenters for Disease Control and Prevention, Kigali, Rwanda.
Eugenie KayirangwaCenters for Disease Control and Prevention, Kigali, Rwanda.
Salomon MutsinziNational Institute of Statistics Rwanda, Kigali, Rwanda.
Alice BayinganaInstitute of HIV/AIDS Disease Prevention and Control, Rwanda Biomedical Center, Kigali, Rwanda.
Placidie MugwanezaInstitute of HIV/AIDS Disease Prevention and Control, Rwanda Biomedical Center, Kigali, Rwanda.
Jean Baptiste T KoamaCenters for Disease Control and Prevention, Kigali, Rwanda.
Rwanda Biomedical Center · RWHarvard University · USUniversity of Rwanda · RW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHIV infection is linked to decreased fertility and fertility desires in sub-Saharan Africa due to biological and social factors. We investigate the relationship between HIV infection and fertility or fertility desires in the context of universal access to antiretroviral therapy introduced in 2004 in Rwanda.

methodsWe used data from 3532 and 4527 women aged 20-49 from the 2005 and 2010 Rwandan Demographic and Health Surveys (RDHS), respectively. The RDHSs included blood-tests for HIV, as well as detailed interviews about fertility, demographic and behavioral outcomes. In both years, multiple logistic regression was used to assess the association between HIV and fertility outcomes within three age categories (20-29, 30-39 and 40-49 years), controlling for confounders and compensating for the complex survey design.

resultsIn 2010, we did not find a difference in the odds of pregnancy in the last 5 years between HIV-seropositive and HIV-seronegative women after controlling for potential biological and social confounders. Controlling for the same confounders, we found that HIV-seropositive women under age 40 were less likely to desire more children compared to HIV-seronegative women (20-29 years adjusted odds ratio (AOR) = 0.31, 95% CI: 0.17, 0.58; 30-39 years AOR = 0.24, 95% CI: 0.14, 0.43), but no difference was found among women aged 40 or older. No associations between HIV and fertility or fertility desire were found in 2005.

conclusionsThese findings suggest no difference in births or current pregnancy among HIV-seropositive and HIV-seronegative women. That in 2010 HIV-seropositive women in their earlier childbearing years desired fewer children than HIV-seronegative women could suggest more women with HIV survived; and stigma, fear of transmitting HIV, or realism about living with HIV and prematurely dying from HIV may affect their desire to have children. These findings emphasize the importance of delivering appropriate information about pregnancy and childbearing to HIV-infected women, enabling women living with HIV to make informed decisions about their reproductive life.

Indexed as

FertilityHealth Knowledge, Attitudes, PracticeAdolescentAdultAnti-HIV AgentsAttitude to HealthCross-Sectional StudiesFemaleHIV-1HIV InfectionsHumansInfectious Disease Transmission, VerticalMiddle AgedPregnancyPregnancy Complications, InfectiousRwandaAnti-HIV AgentsAfricaDHSEvaluationPMTCTWomen’s health

Identifiers

PMID28292306
PMCPMC5351174
OpenAlexW2596036914

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.