Evidence map›Paper›PMID 28292297›Full record

ArticleCardiovascular diabetology2017

Subclinical left ventricular diastolic dysfunction and incident type 2 diabetes risk: the Korean Genome and Epidemiology Study.

Juri Park, Jin-Seok Kim, Seong Hwan Kim, Sunwon Kim, Sang Yup Lim, Hong-Euy Lim, Goo-Yeong Cho, Ki-Chul Sung, Jang-Young Kim, Inkyung Baik and 4 more

Open access · goldAbstract read
In one paragraph

Article in Cardiovascular diabetology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 9 institutions in 1 country.

Juri ParkDepartment of Endocrinology, Hallym University Kangdong Sacred Heart Hospital, Seoul, South Korea.
Jin-Seok KimDepartment of Cardiology, Korea University Ansan Hospital, Ansan, South Korea.
Seong Hwan KimDepartment of Cardiology, Korea University Ansan Hospital, Ansan, South Korea. cardioguy@korea.ac.kr.ORCID 0000-0002-8019-2713
Sunwon KimDepartment of Cardiology, Korea University Ansan Hospital, Ansan, South Korea.
Sang Yup LimDepartment of Cardiology, Korea University Ansan Hospital, Ansan, South Korea.
Hong-Euy LimCardiovascular Center, Korea University Guro Hospital, Seoul, South Korea.
Goo-Yeong ChoDepartment of Cardiology, Seoul National University Bundang Hospital, Seongnam, South Korea.
Ki-Chul SungDepartment of Cardiology, Kangbuk Samsung Hospital, Seoul, South Korea.
Jang-Young KimDepartment of Cardiology, Wonju College of Medicine, Yonsei University, Wonju, South Korea.
Inkyung BaikDepartment of Foods and Nutrition, Kookmin University, Seoul, South Korea.
Kwang Kon KohDepartment of Cardiology, Gachon University Gil Medical Center, Incheon, South Korea.
Jung Bok LeeDepartment of Clinical Epidemiology and Biostatistics, Asan Medical Center, Seoul, South Korea.
Seung Ku LeeInstitute of Human Genomic Study, Korea University Ansan Hospital, Ansan, South Korea.
Chol ShinInstitute of Human Genomic Study, Korea University Ansan Hospital, Ansan, South Korea.
Korea University · KRYonsei University · KRAsan Medical Center · KRGachon University Gil Medical Center · KRHallym University · KRKangbuk Samsung Hospital · KRKookmin University · KRKorea University Medical Center · KRSeoul National University Bundang Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSubclinical left ventricular (LV) diastolic dysfunction in type 2 diabetes (T2D) is a common finding and represents an early sign of diabetic cardiomyopathy. However, the relationship between LV diastolic dysfunction and the incident T2D has not been previously studied.

methodsA total of 1817 non-diabetic participants (mean age, 54 years; 48% men) from the Korean Genome and Epidemiology Study who were free of cardiovascular disease were studied. LV structure and function were assessed by conventional echocardiography and tissue Doppler imaging. Subclinical LV diastolic dysfunction was defined using age-specific cutoff limits for early diastolic (Em) velocity, mitral E/Em ratio, and left atrial volume index.

resultsDuring the 6-year follow-up period, 273 participants (15%) developed T2D. Participants with incident T2D had greater LV mass index (86.7 ± 16.4 vs. 91.2 ± 17.0 g/m

conclusionsIn a community-based cohort, the presence of subclinical LV diastolic dysfunction was a predictor of the progression to T2D. These data suggest that the echocardiographic assessment of LV diastolic function may be helpful in identifying non-diabetic subjects at risk of incident T2D.

Indexed as

Cohort StudiesDiabetes Mellitus, Type 2FemaleFollow-Up StudiesGenome, HumanHumansIncidenceMaleMiddle AgedRepublic of KoreaRisk FactorsVentricular Dysfunction, LeftCohortDiastolic dysfunctionLeft ventricleTissue Doppler echocardiographyType 2 diabetes

Identifiers

PMID28292297
PMCPMC5351106
OpenAlexW2600409463

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.