Observational studyInternational journal of cardiology2017
Systolic-diastolic hypertension versus isolated systolic hypertension and incident heart failure in older adults: Insights from the Cardiovascular Health Study.
Observational study in International journal of cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 40 citations in OpenAlex.
- Alcohol Consumption Patterns and Traditional Beverages Associated with Hypertension Subtypes.Medical sciences (Basel, Switzerland) · 2026Article
- Mortality trends in isolated systolic, diastolic, and combined hypertension: insights from NHANES database.Clinical hypertension · 2026Article
- Adverse Cardiovascular Events Are Infrequent but Significantly Associated With Systolic and Pre-Systolic Hypertension: An Occupational Cohort Study.Cardiology research · 2025Article
- Associations of triglyceride-glucose index and metabolic score for insulin resistance with various hypertension phenotypes in children and adolescents: results from the 2017 China nutrition and health surveillance.Frontiers in endocrinology · 2025Article
- Association between urinary sodium-to-potassium ratio, elevated blood pressure phenotypes and microalbuminuria: Tehran Lipid and Glucose Study.Scientific reports · 2024Article
- Effectiveness of the knowledge, attitude, practice intervention model in the management of hypertension in the elderly.Journal of clinical hypertension (Greenwich, Conn.) · 2024Article
- Prognostic Value of Hemoglobin Concentration on Renal Outcomes with Diabetic Kidney Disease: A Retrospective Cohort Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024Article
- Predictive performance of triglyceride glucose index (TyG index) to identify glucose status conversion: a 5-year longitudinal cohort study in Chinese pre-diabetes people.Journal of translational medicine · 2023Article
- Heart Disease and Stroke Statistics-2023 Update: A Report From the American Heart Association.Circulation · 2023Review
- A year in heart failure: an update of recent findings.ESC heart failure · 2021Review
- Heart Disease and Stroke Statistics-2021 Update: A Report From the American Heart Association.Circulation · 2021Article
- Vascular Stiffness in Aging and Disease.Frontiers in physiology · 2021Review
- Recruiting Student Health Coaches to Improve Digital Blood Pressure Management: Randomized Controlled Pilot Study.JMIR formative research · 2020Article
- Article
- Blood Pressure and Mortality: Joint Effect of Blood Pressure Measures.Journal of clinical cardiology and cardiovascular therapy · 2020Article
- Prevalence and Associated Factors of Hypertension Subtypes Among the Adult Population in Nepal: Evidence from Demographic and Health Survey Data.Osong public health and research perspectives · 2019Article
- Blood Pressure Change from Normal to 2017 ACC/AHA Defined Stage 1 Hypertension and Cardiovascular Risk.Journal of clinical medicine · 2019Article
- Hypertension Management in the Elderly: What is the Optimal Target Blood Pressure?Heart views : the official journal of the Gulf Heart AssociationReview
Corrections and comments
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- Erratum issued
Authors and funding
20 authors at 14 institutions in 4 countries.
Funding
Abstract
backgroundIsolated systolic hypertension (ISH) is common in older adults and is a risk factor for incident heart failure (HF). We examined the association of systolic-diastolic hypertension (SDH) with incident HF and other outcomes in older adults.
methodsIn the Cardiovascular Health Study (CHS), 5776 community-dwelling adults≥65years had data on baseline systolic and diastolic blood pressure (SBP and DBP). We excluded those with DBP<60mmHg (n=821), DBP≥90 and SBP<140mmHg (n=28), normal BP, taking anti-hypertensive drugs (n=1138), normal BP, not taking anti-hypertensive drugs, history of hypertension (n=193), and baseline HF (n=101). Of the remaining 3495, 1838 had ISH (SBP≥140 and DBP<90mmHg) and 240 had SDH (SBP≥140 and DBP≥90mmHg). The main outcome was centrally-adjudicated incident HF over 13years of follow-up.
resultsParticipants had a mean (±SD) age of 73 (±6)years, 57% were women, and 16% African American. Incident HF occurred in 25%, 22% and 11% of participants with ISH, SDH and no hypertension, respectively. Compared to no hypertension, multivariable-adjusted hazard ratios (HR) and 95% confidence intervals (CI) for incident HF associated with ISH and SDH were 1.86 (1.51-2.30) and 1.73 (1.23-2.42), respectively. Cardiovascular mortality occurred in 22%, 24% and 9% of those with ISH, SDH and no hypertension, respectively with respective multivariable-adjusted HRs (95% CIs) of 1.88 (1.49-2.37) and 2.30 (1.64-3.24).
conclusionAmong older adults with hypertension, both SDH and ISH have similar associations with incident HF and cardiovascular mortality.
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