Evidence map›Paper›PMID 28291262›Full record

Trial reportTranslational psychiatry2017

Effects of bumetanide on neurobehavioral function in children and adolescents with autism spectrum disorders.

E Lemonnier, N Villeneuve, S Sonie, S Serret, A Rosier, M Roue, P Brosset, M Viellard, D Bernoux, S Rondeau and 3 more

Erratum issuedOpen access · goldAbstract readClinical Trial, Phase IIMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Translational psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 96 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
96citing papers in PubMed, 5 pooled it
12.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

96 citing papers in PubMed, 5 syntheses or guidelines pooled it, 207 citations in OpenAlex.

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36 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 1 country.

E LemonnierCHU hoputal Le Cluzeau, CHU Limoges, Limoges, France.
N VilleneuveCHU hoputal Le Cluzeau, Hôpital Sainte Marguerite, Marseille, France.
S SonieCHU hoputal Le Cluzeau, CHU le Vinatier, Bron, France.
S SerretCHU hoputal Le Cluzeau, CHU Lenval, Nice, France.
A RosierCHU hoputal Le Cluzeau, CHU Le Rouvray, Sotteville les Rouen, France.
M RoueCHU hoputal Le Cluzeau, CHRU Brest, Brest, France.
P BrossetCHU hoputal Le Cluzeau, CHU Limoges, Limoges, France.
M ViellardCHU hoputal Le Cluzeau, Hôpital Sainte Marguerite, Marseille, France.
D BernouxCHU hoputal Le Cluzeau, CHU le Vinatier, Bron, France.
S RondeauCHU hoputal Le Cluzeau, CHU Le Rouvray, Sotteville les Rouen, France.
S ThummlerCHU hoputal Le Cluzeau, CHU Lenval, Nice, France.
D RavelCHU hoputal Le Cluzeau, Neurochlore Research Team, Marseille, France.
Y Ben-AriCHU hoputal Le Cluzeau, Neurochlore Research Team, Marseille, France.
Centre Hospitalier du Rouvray · FRCentre Hospitalier Le Vinatier · FRCentre Hospitalier Universitaire de Limoges · FRFondation Lenval · FRHôpital Sainte-Marguerite · FRAix-Marseille Université · FRCentre Hospitalier Régional Universitaire de Brest · FRNeurochlore (France) · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In animal models of autism spectrum disorder (ASD), the NKCC1 chloride-importer inhibitor bumetanide restores physiological (Cl

Indexed as

AdolescentAnorexiaAstheniaAutism Spectrum DisorderBumetanideChildChild, PreschoolDehydrationDose-Response Relationship, DrugFemaleHumansHypokalemiaMaleSodium Potassium Chloride Symporter InhibitorsTreatment OutcomeBumetanideSodium Potassium Chloride Symporter Inhibitors

Identifiers

PMID28291262
PMCPMC5416661
OpenAlexW2606925384

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.