Evidence map›Paper›PMID 28290554›Full record

ArticleScientific reports2017

The core protein of a pestivirus protects the incoming virus against IFN-induced effectors.

Christiane Riedel, Benjamin Lamp, Benedikt Hagen, Stanislav Indik, Till Rümenapf

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Christiane RiedelInstitute of Virology, Vetmeduni Vienna, Veterinärplatz 1, 1210 Vienna, Austria.
Benjamin LampInstitute of Virology, Vetmeduni Vienna, Veterinärplatz 1, 1210 Vienna, Austria.
Benedikt HagenInstitute of Virology, Vetmeduni Vienna, Veterinärplatz 1, 1210 Vienna, Austria.
Stanislav IndikInstitute of Virology, Vetmeduni Vienna, Veterinärplatz 1, 1210 Vienna, Austria.
Till RümenapfInstitute of Virology, Vetmeduni Vienna, Veterinärplatz 1, 1210 Vienna, Austria.
University of Veterinary Medicine Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A multitude of viral factors - either inhibiting the induction of the IFN-system or its effectors - have been described to date. However, little is known about the role of structural components of the incoming virus particle in protecting against IFN-induced antiviral factors during or immediately after entry. In this study, we take advantage of the previously reported property of Classical swine fever virus (family Flaviviridae, genus Pestivirus) to tolerate a deletion of the core protein if a compensatory mutation is present in the NS3-helicase-domain (Vp447

Indexed as

AnimalsClassical Swine Fever VirusDNA VirusesPestivirusPestivirus InfectionsSwineViral Core ProteinsVirus ReplicationViral Core Proteins

Identifiers

PMID28290554
PMCPMC5349576
OpenAlexW2651842883

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.