ArticleScientific reports2017
Ndrg3 gene regulates DSB repair during meiosis through modulation the ERK signal pathway in the male germ cells.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 14 citations in OpenAlex.
- Same Sex Chromosomes With Independent Origins in Haplochromine Cichlids.Genome biology and evolution · 2026Article
- Lactate Promotes the Second Cell Fate Decision in Blastocysts by Prompting Primitive Endoderm Formation Through an Intercellular Positive Feedback Loop That Couples Paracrine FGF Signalling.Cell proliferation · 2025Article
- Relationship between serum NDRG3 and papillary thyroid carcinoma.Frontiers in endocrinology · 2022Article
- A novel posttranslational modification of histone, H3 S-sulfhydration, is down-regulated in asthenozoospermic sperm.Journal of assisted reproduction and genetics · 2021Article
- High expression of NDRG3 in osteoarthritis patients.Arthroplasty (London, England) · 2021Article
- UHRF1-repressed 5'-hydroxymethylcytosine is essential for the male meiotic prophase I.Cell death & disease · 2020Article
- Structural and Biophysical Analyses of Human N-Myc Downstream-Regulated Gene 3 (NDRG3) Protein.Biomolecules · 2020Article
- Association of UHRF1 gene polymorphisms with oligospermia in Chinese males.Journal of assisted reproduction and genetics · 2019Article
- CDK2 regulates the NRF1/The Journal of cell biology · 2019Article
- NDRG3 facilitates colorectal cancer metastasis through activating Src phosphorylation.OncoTargets and therapy · 2018Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The N-myc downstream regulated gene (NDRG) family consists of 4 members, NDRG-1, -2, -3, -4. Physiologically, we found Ndrg3, a critical gene which led to homologous lethality in the early embryo development, regulated the male meiosis in mouse. The expression of Ndrg3 was enhanced specifically in germ cells, and reached its peak level in the pachytene stage spermatocyte. Haplo-insufficiency of Ndrg3 gene led to sub-infertility during the male early maturation. In the Ndrg3
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