ArticleScientific reports2017
Chemometric analysis reveals links in the formation of fragrant bio-molecules during agarwood (Aquilaria malaccensis) and fungal interactions.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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19 citing papers in PubMed, 83 citations in OpenAlex.
- Dynamic regulation of secondary metabolites and agarwood aroma compounds inFrontiers in plant science · 2026Article
- Metabolites associated with endophytic fungi in agarwood: fungal compounds and host metabolites triggered by fungi.Mycology · 2026Review
- Dynamic Environmental Interactions Shape the Volatile Compounds of Agarwood Oils Extracted fromMolecules (Basel, Switzerland) · 2025Article
- Visualization OPLS class models of GC-MS-based metabolomics data for identifying agarwood essential oil extracted by hydro-distillation.Scientific reports · 2025Article
- Article
- Article
- Enzyme Activity of Culturable Fungi and Bacteria Isolated from Traditional Agarwood Fermentation Basin Indicate Temporally Significant Lignocellulosic and Lipid Substrate Modulations.Indian journal of microbiology · 2024Article
- Fungal-Bacterial Combinations in Plant Health under Stress: Physiological and Biochemical Characteristics of the Filamentous FungusMicroorganisms · 2024Article
- Physiological characteristics during the formation of aromatic components in xylem ofFrontiers in plant science · 2024Article
- Anatomical, chemical and endophytic fungal diversity of a Qi-Nan clone ofFrontiers in plant science · 2024Article
- Aromatic components and endophytic fungi during the formation of agarwood inFrontiers in microbiology · 2024Article
- Progressive Vertical and Horizontal Phytocompound Changes during Agarwood Formation inLife (Basel, Switzerland) · 2023Article
- Isolation and Characterization of Bacteria and Fungi Associated with Agarwood Fermentation.Current microbiology · 2022Article
- Agarwood-The Fragrant Molecules of a Wounded Tree.Molecules (Basel, Switzerland) · 2022Review
- Effects of various artificial agarwood-induction techniques on the metabolome of Aquilaria sinensis.BMC plant biology · 2021Article
- Genome-wide detection and classification of terpene synthase genes inPhysiology and molecular biology of plants : an international journal of functional plant biology · 2021Article
- Methyl jasmonate and crude extracts ofHeliyon · 2021Article
- The Scent of Stress: Evidence From the Unique Fragrance of Agarwood.Frontiers in plant science · 2019Review
- α-Glucosidase Inhibition and Antibacterial Activity of Secondary Metabolites from the Ecuadorian Species Clinopodium taxifolium (Kunth) Govaerts.Molecules (Basel, Switzerland) · 2018Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fragrant agarwood, arguably the costliest wood in the world, is formed by plant-fungal interactions in Aquilaria spp. However, very little is known about this fragrant outcome of interaction. Therefore, mimicking the ancient traditions of agarwood production in Assam (Northeast India), a chemometric assessment of the agarwood-fungus interaction was made by chemical profiling (GC-MS) coupled with statistical analysis (principal component, correlation network analysis) across three platforms, viz. callus, juvenile plants and resinous wood-chips with an associated Fusarium. In the study of callus-fungus interaction, increased accumulation of key aroma compounds such as pentatriacontane {fold change (log2FC) = 3.47)}, 17-pentatriacontene (log2FC = 2.95), tetradecane, 2-methyl- (log2FC = 1.10) over callus and activation of pathways related to defense and secondary metabolism indicated links to aroma production. Study on fungal interactions in juvenile plants and resinous wood-chips indicated formation of terpenoid precursors (e.g. farnesol, geranylgeraniol acetate) and agarwood sesquiterpenes (e.g. agarospirol, γ-eudesmol). Correlation network analysis revealed the possible regulation of sesquiterpene biosynthesis involving squalene. Also a direct role of fungus in aroma (e.g. dodecane, 4-methyl-, tetracosane) was highlighted. Appearance of fragrant molecules unknown to agarwood during interaction featured as a new possibility for future research.
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