ArticleNature communications2017
Palladium-catalysed synthesis of triaryl(heteroaryl)methanes.
Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Aromatic or Hetero-aromatic Directly Attached Tri and Tetrasubstituted Methanes: New Chemical Entities as Anti-Infectives.Current medicinal chemistry · 2023Article
- Unified synthesis of multiply arylated alkanes by catalytic deoxygenative transformation of diarylketones.Chemical science · 2022Article
- Organocatalytic asymmetric formal oxidative coupling for the construction of all-aryl quaternary stereocenters.Chemical science · 2021Article
- Benzylic Methylene Functionalizations of Diarylmethanes.Chemistry, an Asian journal · 2020Review
- Migratory functionalization of unactivated alkyl bromides for construction of all-carbon quaternary centers via transposed tert-C-radicals.Nature communications · 2020Article
- Cyclopentyl Methyl Ether: An Elective Ecofriendly Ethereal Solvent in Classical and Modern Organic Chemistry.ChemSusChem · 2019Review
- One-pot aminobenzylation of aldehydes with toluenes.Nature communications · 2018Article
- Palladium-Catalyzed Triarylation of spAdvanced synthesis & catalysis · 2018Article
- Synthesis of Diarylated 4-Pyridylmethyl Ethers via Palladium-Catalyzed Cross-Coupling Reactions.Advanced synthesis & catalysis · 2017Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Tetraarylmethane derivatives are desirable for a variety of applications, but difficult to access with modern C-C bond-forming reactions. Here we report a straightforward method for palladium-catalysed arylation of aryl(heteroaryl)methanes and diaryl(heteroaryl)methanes with aryl chlorides. This reaction enables introduction of various aryl groups to construct triaryl(heteroaryl)methanes via a C-H functionalization in good to excellent yield, and represents the first step towards a general transition metal catalysed synthesis of tetraarylmethanes.
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Registered trials
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