Evidence map›Paper›PMID 28290214›Full record

ArticleComputer methods in biomechanics and biomedical engineering2017

Computational study of cell adhesion and rolling in flow channel by meshfree method.

Liqiang Lin, Xiaowei Zeng

Abstract read
In one paragraph

Article in Computer methods in biomechanics and biomedical engineering, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Liqiang Lina Department of Mechanical Engineering , University of Texas at San Antonio , San Antonio , TX , USA.
Xiaowei Zenga Department of Mechanical Engineering , University of Texas at San Antonio , San Antonio , TX , USA.

Funding

Numerical Investigation of Collective Cell MigrationSC2GM112575 · NIGMS · UNIVERSITY OF TEXAS SAN ANTONIO · PI ZENG, XIAOWEI · 2015 to 2017
$441k
NIGMS NIH HHS SC2 GM112575
6 · The paper itself

Abstract

Tethering and rolling of circulating leukocytes on the surface of endothelium are critical steps during an inflammatory response. A soft solid cell model was proposed to study monocytes tethering and rolling behaviors on substrate surface in shear flow. The interactions between monocytes and micro-channel surface were modeled by a coarse-grained molecular adhesive potential. The computational model was implemented in a Lagrange-type meshfree Galerkin formulation to investigate the monocyte tethering and rolling process with different flow rates. From the simulation results, it was found that the flow rate has profound effects on the rolling velocity, contact area and effective stress of monocytes. As the flow rate increased, the rolling velocity would increase linearly, whereas the contact area and average effective stress in monocyte showed nonlinear increase.

Indexed as

Computer SimulationRheologyAccelerationAlgorithmsCell AdhesionHumansLeukocyte RollingLeukocytesMonocytesNumerical Analysis, Computer-Assistedcell rollingCell tetheringhuman monocytemeshfree methodnumerical simulationshear flow

Identifiers

PMID28290214
PMCPMC5569581

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.