Evidence map›Paper›PMID 28290206›Full record

ReviewACS nano2017

Diverse Applications of Nanomedicine.

Beatriz Pelaz, Christoph Alexiou, Ramon A Alvarez-Puebla, Frauke Alves, Anne M Andrews, Sumaira Ashraf, Lajos P Balogh, Laura Ballerini, Alessandra Bestetti, Cornelia Brendel and 76 more

Abstract readReview
In one paragraph

Review in ACS nano, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 420 papers.

0numbers the graph read from it
0cells of the map it votes in
420citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

420 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Navigating theNanoscale advances · 2026
    Review
  17. Review
  18. Article
  19. SonoPIN enables precise, noninvasive, and efficient intracellular delivery of PROTACs.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  20. Review

360 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

86 authors.

Christoph AlexiouENT-Department, Section of Experimental Oncology & Nanomedicine (SEON), Else Kröner-Fresenius-Stiftung-Professorship for Nanomedicine, University Hospital Erlangen , 91054 Erlangen, Germany.
Ramon A Alvarez-PueblaDepartment of Physical Chemistry, Universitat Rovira I Virgili , 43007 Tarragona, Spain.ORCID 0000-0003-4770-5756
Frauke AlvesDepartment of Molecular Biology of Neuronal Signals, Max-Planck-Institute for Experimental Medicine , 37075 Göttingen, Germany.
Sumaira Ashraf
Lajos P BaloghAA Nanomedicine & Nanotechnology Consultants , North Andover, Massachusetts 01845, United States.
Laura BalleriniInternational School for Advanced Studies (SISSA/ISAS) , 34136 Trieste, Italy.ORCID 0000-0001-8420-0787
Alessandra BestettiSchool of Chemistry & Bio21 Institute, University of Melbourne , Parkville, Victoria 3010, Australia.
Cornelia Brendel
Susanna BosiDepartment of Chemical and Pharmaceutical Sciences, University of Trieste , 34127 Trieste, Italy.
Monica CarrilCIC biomaGUNE , Paseo de Miramón 182, 20014, Donostia - San Sebastián, Spain.ORCID 0000-0002-1232-8658
Warren C W ChanInstitute of Biomaterials and Biomedical Engineering, University of Toronto , Toronto, Ontario M5S 3G9, Canada.ORCID 0000-0001-5435-4785
Chunying ChenCAS Center for Excellence in Nanoscience and CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology of China , Beijing 100190, China.ORCID 0000-0002-6027-0315
Xiaodong ChenSchool of Materials Science and Engineering, Nanyang Technological University , Singapore 639798.ORCID 0000-0002-3312-1664
Xiaoyuan ChenLaboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health , Bethesda, Maryland 20892, United States.ORCID 0000-0002-9622-0870
Zhen ChengMolecular Imaging Program at Stanford and Bio-X Program, Canary Center at Stanford for Cancer Early Detection, Stanford University , Stanford, California 94305, United States.
Daxiang CuiInstitute of Nano Biomedicine and Engineering, Department of Instrument Science and Engineering, School of Electronic Information and Electronical Engineering, National Center for Translational Medicine, Shanghai Jiao Tong University , 200240 Shanghai, China.
Jianzhong DuDepartment of Polymeric Materials, School of Materials Science and Engineering, Tongji University , Shanghai, China.ORCID 0000-0003-1889-5669
Christian Dullin
Alberto EscuderoInstituto de Ciencia de Materiales de Sevilla. CSIC, Universidad de Sevilla , 41092 Seville, Spain.ORCID 0000-0002-0850-6589
Neus FeliuDepartment of Clinical Science, Intervention, and Technology (CLINTEC), Karolinska Institutet , 141 86 Stockholm, Sweden.
Mingyuan GaoInstitute of Chemistry, Chinese Academy of Sciences , 100190 Beijing, China.ORCID 0000-0002-7360-3684
Michael GeorgeNanion , 80636 München, Germany.
Yury GogotsiDepartment of Materials Science and Engineering and A.J. Drexel Nanomaterials Institute, Drexel University , Philadelphia, Pennsylvania 19104, United States.ORCID 0000-0001-9423-4032
Arnold Grünweller
Zhongwei GuCollege of Polymer Science and Engineering, Sichuan University , 610000 Chengdu, China.ORCID 0000-0003-1547-6880
Naomi J HalasDepartments of Physics and Astronomy, Rice University , Houston, Texas 77005, United States.ORCID 0000-0002-8461-8494
Roland K Hartmann
Mark C HersamDepartments of Materials Science and Engineering, Chemistry, and Medicine, Northwestern University , Evanston, Illinois 60208, United States.ORCID 0000-0003-4120-1426
Patrick HunzikerUniversity Hospital , 4056 Basel, Switzerland.
Xingyu JiangCAS Center for Excellence in Nanoscience and CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology of China , Beijing 100190, China.ORCID 0000-0002-5008-4703
Philipp JungebluthThoraxklinik Heidelberg, Universitätsklinikum Heidelberg , 69120 Heidelberg, Germany.
Pranav KadhiresanInstitute of Biomaterials and Biomedical Engineering, University of Toronto , Toronto, Ontario M5S 3G9, Canada.
Kazunori KataokaThe University of Tokyo , Bunkyo, Tokyo 113-8654, Japan.
Ali KhademhosseiniHavard University , Cambridge, Massachusetts 02139, United States.ORCID 0000-0002-2692-1524
Jindřich KopečekBiomedical Polymers Laboratory, University of Utah , Salt Lake City, Utah 84112, United States.ORCID 0000-0002-4451-6944
Nicholas A KotovEmergency Medicine, University of Michigan , Ann Arbor, Michigan 48019, United States.ORCID 0000-0002-6864-5804
Harald F KrugEMPA, Federal Institute for Materials Science and Technology , CH-9014 St. Gallen, Switzerland.
Dong Soo Lee
Claus-Michael LehrDepartment of Pharmacy, Saarland University , 66123 Saarbrücken, Germany.
Kam W LeongDepartment of Biomedical Engineering, Columbia University , New York City, New York 10027, United States.
Xing-Jie LiangCAS Center for Excellence in Nanoscience and CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology of China , Beijing 100190, China.ORCID 0000-0002-4793-1705
Mei Ling LimDepartment of Clinical Science, Intervention, and Technology (CLINTEC), Karolinska Institutet , 141 86 Stockholm, Sweden.
Luis M Liz-MarzánCIC biomaGUNE , Paseo de Miramón 182, 20014, Donostia - San Sebastián, Spain.ORCID 0000-0002-6647-1353
Xiaowei MaLaboratory of Controllable Nanopharmaceuticals, Chinese Academy of Sciences (CAS) , 100190 Beijing, China.
Paolo MacchiariniLaboratory of Bioengineering Regenerative Medicine (BioReM), Kazan Federal University , 420008 Kazan, Russia.
Huan Meng
Helmuth MöhwaldDepartment of Interfaces, Max-Planck Institute of Colloids and Interfaces , 14476 Potsdam, Germany.
Paul MulvaneySchool of Chemistry & Bio21 Institute, University of Melbourne , Parkville, Victoria 3010, Australia.ORCID 0000-0002-8007-3247
Andre E Nel
Shuming NieEmory University , Atlanta, Georgia 30322, United States.ORCID 0000-0002-7328-1144
Peter NordlanderDepartments of Physics and Astronomy, Rice University , Houston, Texas 77005, United States.ORCID 0000-0002-1633-2937
Teruo OkanoTokyo Women's Medical University , Tokyo 162-8666, Japan.
Jose OliveiraSMALL, Wiley-VCH , Weinheim, German.
Tai Hyun ParkAdvanced Institutes of Convergence Technology , Suwon, South Korea.ORCID 0000-0003-4254-0657
Reginald M PennerDepartment of Chemistry, University of California , Irvine, California 92697, United States.ORCID 0000-0003-2831-3028
Maurizio PratoDepartment of Chemical and Pharmaceutical Sciences, University of Trieste , 34127 Trieste, Italy.
Victor PuntesICREA , Pg. Lluís Companys 23, 08010 Barcelona, Spain.
Vincent M RotelloDepartment of Chemistry, University of Massachusetts , Amherst, Massachusetts 01003, United States.ORCID 0000-0002-5184-5439
Amila SamarakoonInstitute of Biomaterials and Biomedical Engineering, University of Toronto , Toronto, Ontario M5S 3G9, Canada.
Raymond E SchaakDepartment of Chemistry, The Pennsylvania State University , University Park, Pennsylvania 16802, United States.ORCID 0000-0002-7468-8181
Sebastian SjöqvistDepartment of Clinical Science, Intervention, and Technology (CLINTEC), Karolinska Institutet , 141 86 Stockholm, Sweden.
Andre G SkirtachDepartment of Interfaces, Max-Planck Institute of Colloids and Interfaces , 14476 Potsdam, Germany.
Mahmoud G Soliman
Molly M StevensDepartment of Materials, Department of Bioengineering, Institute for Biomedical Engineering, Imperial College London , London SW7 2AZ, United Kingdom.ORCID 0000-0002-7335-266X
Hsing-Wen SungDepartment of Chemical Engineering and Institute of Biomedical Engineering, National Tsing Hua University , Hsinchu City, Taiwan, ROC 300.
Ben Zhong TangHong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction , Hong Kong, China.
Rainer TietzeENT-Department, Section of Experimental Oncology & Nanomedicine (SEON), Else Kröner-Fresenius-Stiftung-Professorship for Nanomedicine, University Hospital Erlangen , 91054 Erlangen, Germany.
Buddhisha N UdugamaInstitute of Biomaterials and Biomedical Engineering, University of Toronto , Toronto, Ontario M5S 3G9, Canada.
J Scott VanEppsEmergency Medicine, University of Michigan , Ann Arbor, Michigan 48019, United States.ORCID 0000-0002-5437-3123
Tanja WeilInstitut für Organische Chemie, Universität Ulm , 89081 Ulm, Germany.ORCID 0000-0002-5906-7205
Itamar WillnerInstitute of Chemistry, The Center for Nanoscience and Nanotechnology, The Hebrew University of Jerusalem , Jerusalem 91904, Israel.ORCID 0000-0001-9710-9077
Yuzhou WuMax-Planck-Institute for Polymer Research , 55128 Mainz, Germany.
Lily YangSMALL, Wiley-VCH , Weinheim, German.
Zhao Yue
Qian Zhang
Qiang ZhangSchool of Pharmaceutical Science, Peking University , 100191 Beijing, China.
Xian-En ZhangNational Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences , 15 Datun Road, Chaoyang District, Beijing, 100101, China.
Yuliang ZhaoCAS Center for Excellence in Nanoscience and CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology of China , Beijing 100190, China.ORCID 0000-0002-9586-9360
Xin ZhouKey Laboratory of Magnetic Resonance in Biological Systems, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences , Wuhan 430071, China.ORCID 0000-0002-5580-7907
Wolfgang J ParakCIC biomaGUNE , Paseo de Miramón 182, 20014, Donostia - San Sebastián, Spain.ORCID 0000-0003-1672-6650

Funding

Tumor Environment and Metastasis (TEAM) Research ProgramP30CA060553 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LEONIDAS C. PLATANIAS · 1993 to 2026
$153.9M
Stroma Breaking Theranostic Nanoparticle for Targeted Pancreatic Cancer TherapyU01CA198913 · NCI · EMORY UNIVERSITY · PI MAO, HUI, YANG, LILY · 2015 to 2019
$3.0M
UCLA Multifunctional Mesoporous Silica Nanoparticle Platform for Treatment of Pancreas CancerU01CA198846 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DONAHUE, TIMOTHY R, MENG, HUAN · 2015 to 2019
$2.4M
Drug-Free Macromolecular TherapeuticsR01GM095606 · NIGMS · UNIVERSITY OF UTAH · PI KOPECEK, JINDRICH H. · 2011 to 2018
$2.3M
NCI NIH HHS P30 CA060553NCI NIH HHS U01 CA198846NCI NIH HHS U01 CA198913NIGMS NIH HHS R01 GM095606
6 · The paper itself

Abstract

The design and use of materials in the nanoscale size range for addressing medical and health-related issues continues to receive increasing interest. Research in nanomedicine spans a multitude of areas, including drug delivery, vaccine development, antibacterial, diagnosis and imaging tools, wearable devices, implants, high-throughput screening platforms, etc. using biological, nonbiological, biomimetic, or hybrid materials. Many of these developments are starting to be translated into viable clinical products. Here, we provide an overview of recent developments in nanomedicine and highlight the current challenges and upcoming opportunities for the field and translation to the clinic.

Indexed as

Drug Delivery SystemsNanomedicineAnimalsDrug CarriersHumansNanoparticlesNanotechnologyNeoplasmsParticle SizeDrug Carriers

Identifiers

PMID28290206
PMCPMC5371978

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.