Evidence map›Paper›PMID 28289894›Full record

Trial reportLasers in medical science2017

The effect of low-level laser therapy on tooth movement during canine distalization.

Sevin Erol Üretürk, Müyesser Saraç, Sönmez Fıratlı, Şule Batu Can, Yegane Güven, Erhan Fıratlı

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Lasers in medical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05469451 (Effect of Diode Laser), which is not on this map. Cited by 32 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 5 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05469451 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Effect of Diode Laser (940nm) on Total Relief of Dental Crowding and Pain Perception in Orthodontics: Randomized Clinical Trial (RCT)

TypeinterventionalSponsorFundación Universitaria CIEORan2022 to 2022Enrolled50ConditionsLow Level Laser Therapy, Pain, Crowding, ToothArmsLow level laser therapy
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 5 syntheses or guidelines pooled it, 67 citations in OpenAlex.

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  6. Effect of low-level laser therapy on en masse retraction in females with bimaxillary dentoalveolar protrusion : A single-center randomized clinical trial.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sevin Erol ÜretürkDepartment of Orthodontics, Faculty of Dentistry, Istanbul University, Istanbul, Turkey. sevinerol@gmail.com.
Müyesser SaraçDepartment of Orthodontics, Faculty of Dentistry, Istanbul University, Istanbul, Turkey.
Sönmez FıratlıDepartment of Orthodontics, Faculty of Dentistry, Istanbul University, Istanbul, Turkey.
Şule Batu CanDepartment of Biochemistry, Faculty of Dentistry, Istanbul University, Istanbul, Turkey.
Yegane GüvenDepartment of Biochemistry, Faculty of Dentistry, Istanbul University, Istanbul, Turkey.
Erhan FıratlıDepartment of Periodontology, Faculty of Dentistry, Istanbul University, Istanbul, Turkey.
Istanbul University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the study is to determine the effects of low level laser therapy on tooth movement during canine distalization by evaluating IL-1β, TGF-β1 levels in gingival crevicular fluid. Maxillary first premolars of the 15 Angle Class II division I patients (12-19 years old) were extracted. Right maxillary canines were distalized by standard protocol as control group whereas the left maxillary canines distalized by laser application. A gallium-aluminum-arsenide diode laser with an output power of 20 mW was applied as five doses from the buccal and the palatal side on the day 0, and the 3rd, 7th, 14th, 21th 30th, 33st, 37th, 60th, 63th, and 67th days. Gingival crevicular fluid samples were obtained with filtration paper at the initial, 7th, 14th, and 21th days, and the IL-1ß and TGF-ß1 cytokine levels were analyzed. Orthodontic models and periodontal indices were taken initially and on the days 30th, 60th, and 90th of canine distalization period. Tooth movement was assessed by scanning models (3Shape). The amount of tooth movement in the laser group was 40% more than the control group. First day IL-1ß levels were statistically higher than initial and 21st day levels (P= 0.003, P = 0.012). The rise in IL-1ß levels caused the negative correlations between 7th day IL-1β and 21st day TGF-β1 levels describes the tissue effects of laser application. Periodontal indices showed no sign of gingival inflammation during canine distalization period. As conclusion, laser does accelerate tooth movement and could shorten the whole treatment duration.

Indexed as

Low-Level Light TherapyAdolescentAdultAnimalsCase-Control StudiesCuspidDental PlaqueFemaleGingival Crevicular FluidHemorrhageHumansInterleukin-1betaLasers, SemiconductorMalePeriodontal IndexTooth MigrationInterleukin-1betaTransforming Growth Factor beta1Canine distalizationIL-1βLow-level laser therapyTGF-βVelocity of orthodontic tooth movement

Identifiers

PMID28289894
OpenAlexW2597093207

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.