ArticleNeuroradiology2017
Imaging characteristics associated with clinical outcomes in posterior reversible encephalopathy syndrome.
Article in Neuroradiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.
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Who cites it
38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 82 citations in OpenAlex.
- Frequency of ischaemic stroke and intracranial haemorrhage in patients with reversible cerebral vasoconstriction syndrome (RCVS) and posterior reversible encephalopathy syndrome (PRES) - A systematic review.European journal of neurology · 2024Pooled it
- Brain MRI findings in COVID-19 patients with PRES: A systematic review.Clinical imaging · 2022Pooled it
- Posterior reversible encephalopathy syndrome in Colombia a case series.Scientific reports · 2026Article
- Posterior Reversible Encephalopathy Syndrome in the Postpartum Period: A Rare Entity With Atypical Presentation.Cureus · 2025Article
- Management of severe acute encephalopathy in the ICU: an expert consensus statement from the french society of intensive care medicine.Annals of intensive care · 2025Review
- Magnetic resonance imaging patterns and perfusion changes of posterior reversible encephalopathy syndrome in children with clinical outcome correlation.Pediatric radiology · 2024Observational
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- Posterior reversible encephalopathy syndrome mimicking subacute ischemic stroke: a case report.Radiology case reports · 2022Article
- A Case of Synthetic Cannabinoid (K2)-Induced Posterior Reversible Encephalopathy Syndrome (PRES).The American journal of case reports · 2022Article
- Posterior Reversible Encephalopathy in Sepsis-Associated Encephalopathy: Experience from a Single Center.Neurocritical care · 2022Observational
- Posterior Reversible Encephalopathy Syndrome and brain haemorrhage as COVID-19 complication: a review of the available literature.Journal of neurology · 2021Review
- Posterior reversible encephalopathy syndrome revealing Takayasu's arteritis in a child.Radiology case reports · 2021Article
- Extensive Brainstem Posterior Reversible Encephalopathy Syndrome in a Hemodialysis Non-Adherent Patient.Cureus · 2021Article
- Predicting 90-day modified Rankin Scale score with discharge information in acute ischaemic stroke patients following treatment.BMJ neurology open · 2021Article
- Cerebrovascular Disease in the Setting of Posterior Reversible Encephalopathy Syndrome.Frontiers in neurology · 2021Review
- Common infectious diseases of the central nervous system-clinical features and imaging characteristics.Quantitative imaging in medicine and surgery · 2020Article
- Brain Imaging of Patients with COVID-19: Findings at an Academic Institution during the Height of the Outbreak in New York City.AJNR. American journal of neuroradiology · 2020Article
- Posterior reversible encephalopathy syndrome in patients with COVID-19.Journal of the neurological sciences · 2020Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
Abstract
purposePosterior reversible encephalopathy syndrome (PRES) is a disorder of cerebrovascular autoregulation that can result in brain edema, hemorrhage, and infarction. We sought to investigate whether certain imaging characteristics in PRES are associated with clinically significant patient outcomes.
methodsWe retrospectively reviewed all cases of PRES occurring between 2008 and 2014 at two major academic medical centers. Demographic, clinical, and radiographic data were collected. We analyzed imaging studies for vasogenic edema, hemorrhage, and diffusion restriction. We performed univariate analysis and stepwise logistic regression to assess the association between our radiologic findings of interest and clinical outcomes as defined by hospital discharge disposition and modified Rankin scale (mRS) at time of discharge.
resultsWe identified 99 cases of PRES in 96 patients. The median age was 55 years (IQR 30-65) and 74% were women. In 99 cases, 60% of patients had active cancer, 19% had history of bone marrow or organ transplantation, 14% had autoimmune disease, and 8% were peripartum. Imaging at clinical presentation showed extensive vasogenic edema in 39%, hemorrhage in 36%, hemorrhage with mass effect in 7%, and restricted diffusion in 16%. In our final logistic regression models, the presence of extensive vasogenic edema, hemorrhage with mass effect, or diffusion restriction was associated with worse clinical outcome as defined by both discharge disposition (OR = 4.3; 95% CI: 1.4-36.3; p = 0.047) and mRS (OR = 3.6; 95% CI: 1.2-10.7; p = 0.019).
conclusionsExtensive vasogenic edema, hemorrhage, and restricted diffusion on initial imaging in PRES are associated with worse clinical outcomes.
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