Evidence map›Paper›PMID 28289795›Full record

ReviewDer Nervenarzt2017

[Pharmacological treatment of motor symptoms in Parkinson's diseases].

W H Jost

Abstract readReview
PubMed Publisher
In one paragraph

Review in Der Nervenarzt, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

W H JostParkinson-Klinik Ortenau, Kreuzbergstr. 12-16, 77709, Wolfach, Deutschland. w.jost@parkinson-klinik.de.
Parkinson-Klinik Ortenau · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the 1960s many substance classes have been introduced for treatment of idiopathic Parkinson's disease. The most important and effective medication is levodopa (L-dopa) always in combination with a decarboxylase inhibitor. In addition, dopamine agonists, monoamine oxidase B (MAO-B) inhibitors, catechol-o-methyltransferase (COMT) inhibitors, N‑methyl-D-aspartate (NMDA) antagonists and very rarely anticholinergics are administered depending on the motor symptoms, age and a multitude of other factors. Fortunately, within the substance classes there are various preparations, which also have different effects. In order that the advantages of the individual medications can be exploited and undesired effects and interactions can be avoided, one must come to terms with the complex data and the pharmacology of the medication. In addition important aspects are interactions and reciprocal actions. In the foreseeable future, different substance classes are to be expected.

Indexed as

Antiparkinson AgentsDopamine AntagonistsDose-Response Relationship, DrugDrug CombinationsDrug MonitoringEvidence-Based MedicineHumansMonoamine Oxidase InhibitorsMovement DisordersParkinson DiseaseTreatment OutcomeAntiparkinson AgentsDopamine AntagonistsDrug CombinationsMonoamine Oxidase InhibitorsCatechol-o-methyltransferase inhibitorDopamine agonistsL-dopaMonoamine oxidase B inhibitorPharmacology

Identifiers

PMID28289795
OpenAlexW2595783337

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.