Evidence map›Paper›PMID 28289550›Full record

ArticleAIP advances2017

Blood clot detection using magnetic nanoparticles.

Hafsa Khurshid, Bruce Friedman, Brent Berwin, Yipeng Shi, Dylan B Ness, John B Weaver

Open access · goldAbstract read
In one paragraph

Article in AIP advances, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Hafsa KhurshidDepartment of Radiology, Dartmouth-Hitchcock Medical Center , Lebanon New Hampshire 03756, USA.
Bruce FriedmanCardiology Department, Dartmouth-Hitchcock Medical Center , Lebanon New Hampshire 03756, USA.
Brent BerwinDepartment of Microbiology and Immunology, Geisel School of Medicine , Hanover New Hampshire 03755, USA.
Yipeng ShiDepartment of Physics & Astronomy, Dartmouth College , Hanover New Hampshire 03755, USA.
Dylan B NessDepartment of Radiology, Dartmouth-Hitchcock Medical Center , Lebanon New Hampshire 03756, USA.
John B Weaver
Dartmouth–Hitchcock Medical Center · USDartmouth College · US

Funding

Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Steven D Leach · 1985 to 2026
$91.3M
Novel Techology for Early Indentification of Surgical InfectionsR21EB021456 · NIBIB · DARTMOUTH-HITCHCOCK CLINIC · PI WEAVER, JOHN B · 2016 to 2017
$446k
NCI NIH HHS P30 CA023108NIBIB NIH HHS R21 EB021456
6 · The paper itself

Abstract

Deep vein thrombosis, the development of blood clots in the peripheral veins, is a very serious, life threatening condition that is prevalent in the elderly. To deliver proper treatment that enhances the survival rate, it is very important to detect thrombi early and at the point of care. We explored the ability of magnetic particle spectroscopy (MSB) to detect thrombus via specific binding of aptamer functionalized magnetic nanoparticles with the blood clot. MSB uses the harmonics produced by nanoparticles in an alternating magnetic field to measure the rotational freedom and, therefore, the bound state of the nanoparticles. The nanoparticles' relaxation time for Brownian rotation increases when bound [A.M. Rauwerdink and J. B. Weaver, Appl. Phys. Lett.

Identifiers

PMID28289550
PMCPMC5315662
OpenAlexW2588716487

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.