ArticleFrontiers in immunology2017
Cytokine Signatures in Mucocutaneous and Ocular Behçet's Disease.
Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 3 of them syntheses that pooled it.
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Who cites it
31 citing papers in PubMed, 3 syntheses or guidelines pooled it, 56 citations in OpenAlex.
- Finding the Needle in the Haystack: Serological and Urinary Biomarkers in Behçet's Disease: A Systematic Review.International journal of molecular sciences · 2023Pooled it
- Behҫet's Disease, and the Role of TNF-α and TNF-α Blockers.International journal of molecular sciences · 2020Pooled it
- Hidradenitis Suppurativa: A Systematic Review Integrating Inflammatory Pathways Into a Cohesive Pathogenic Model.Frontiers in immunology · 2018Pooled it
- SerumInternational journal of molecular sciences · 2026Article
- Genetic analysis of Behçet's disease using whole-exome sequencing and bioinformatics analysis in Korean patients.Frontiers in genetics · 2026Article
- Altered polyunsaturated fatty acids and oxylipins profile in Behçet's disease.The Korean journal of internal medicine · 2025Article
- Advances in the Study of the Pathogenesis of Vogt-Koyanagi- Harada Syndrome.Current molecular medicine · 2025Review
- Neuro-Behçet With a Thalamic Lesion: A Case Report.Cureus · 2023Article
- Cerebrospinal fluid level of neurofilament light chain is associated with increased disease activity in neuro-Behçet's disease.Turkish journal of medical sciences · 2022Article
- Understanding Immune Responses to Viruses-Do Underlying Th1/Th2 Cell Biases Predict Outcome?Viruses · 2022Review
- Carnosine Protects Macrophages against the Toxicity of Aβ1-42 Oligomers by Decreasing Oxidative Stress.Biomedicines · 2021Article
- Serum Interleukin-26 Is a New Biomarker for Disease Activity Assessment in Systemic Lupus Erythematosus.Frontiers in immunology · 2021Article
- Critical Role of Gut Microbiota and Epigenetic Factors in the Pathogenesis of Behçet's Disease.Frontiers in cell and developmental biology · 2021Review
- A Review of the Various Roles and Participation Levels of B-Cells in Non-Infectious Uveitis.Frontiers in immunology · 2021Review
- Association Between Interleukin 35 Gene Single Nucleotide Polymorphisms and the Uveitis Immune Status in a Chinese Han Population.Frontiers in immunology · 2021Article
- Can Unconventional Immunomodulatory Agents Help Alleviate COVID-19 Symptoms and Severity?mSphere · 2020Article
- Modulation of Pro-Oxidant and Pro-Inflammatory Activities of M1 Macrophages by the Natural Dipeptide Carnosine.International journal of molecular sciences · 2020Article
- Tocilizumab in the treatment of severe and refractory parenchymal neuro-Behçet's syndrome: case series and literature review.Therapeutic advances in musculoskeletal disease · 2020Article
- Carnosine Decreases PMA-Induced Oxidative Stress and Inflammation in Murine Macrophages.Antioxidants (Basel, Switzerland) · 2019Article
- Value of hematological indices versus VEGF as biomarkers of activity in Behçet's disease.Clinical rheumatology · 2019Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Behçet's disease (BD) is a multi-systemic inflammatory disorder consisting of recurrent oral aphthosis, genital ulcers, and chronic relapsing bilateral uveitis; however, many other organs may be affected. Several pro-inflammatory cytokines, mainly derived from Th1 and Th17 lymphocytes, seem to be involved in different pathogenic pathways leading to development of the clinical manifestations. On this basis, the primary aim of our study was to compare a core set of pro-inflammatory cytokines between patients with BD and healthy control (HC). The secondary goal was to evaluate potential correlations between these putative circulating biomarkers, the status of disease activity, and the specific organ involvement at the time of sample collection. Fifty-four serum samples were collected from 46 BD patients (17 males, 29 females, mean age 45.5 ± 11.3 years), and 19 HC (10 males, 9 females, mean age 43 ± 8.3 years). Twenty-five serum cytokines (APRIL/TNFS13, BAFF/TNFSF13B, sCD30/TNFRSF8, sCD163, Chitinase3-like1, gp130/sIL-6Rb, IFNb, sIL-6Ra, IL-10, IL-11, IL-19, IL-20, IL-26, IL-27 (p28), IL-28A/IFN-lambda2, IL-29/IFN-lambda1, IL-32, IL-34, IL-35, LIGHT/TNFSF-14, Pentraxin-3, sTNF-R1, sTNF-R2, TSLP, and TWEAK/TNFSF-12) were simultaneously quantified using a Bio-Rad cytokine bead arrays. Serum concentration of sTNF-R1 (
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.