Evidence map›Paper›PMID 28289391›Full record

ArticleFrontiers in pharmacology2017

Cannabidiol Affects MK-801-Induced Changes in the PPI Learned Response of Capuchin Monkeys (

Patricia G Saletti, Rafael S Maior, Marilia Barros, Hisao Nishijo, Carlos Tomaz

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Patricia G SalettiPrimate Center and Laboratory of Neurosciences and Behavior, Department of Physiological Sciences, Institute of Biology, University of Brasilia Brasilia, Brazil.
Rafael S MaiorPrimate Center and Laboratory of Neurosciences and Behavior, Department of Physiological Sciences, Institute of Biology, University of BrasiliaBrasilia, Brazil; Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institutet, Karolinska University HospitalStockholm, Sweden.
Marilia BarrosDepartment of Pharmaceutical Sciences, School of Health Sciences, University of Brasilia Brasilia, Brazil.
Hisao NishijoSystem Emotional Science, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama Toyama, Japan.
Carlos TomazPrimate Center and Laboratory of Neurosciences and Behavior, Department of Physiological Sciences, Institute of Biology, University of BrasiliaBrasilia, Brazil; Neuroscience Research Group, University CEUMASão Luís, Brazil.
Universidade de Brasília · BRKarolinska University Hospital · SEUniversity of Toyama · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There are several lines of evidence indicating a possible therapeutic action of cannabidiol (CBD) in schizophrenia treatment. Studies with rodents have demonstrated that CBD reverses MK-801 effects in prepulse inhibition (PPI) disruption, which may indicate that CBD acts by improving sensorimotor gating deficits. In the present study, we investigated the effects of CBD on a PPI learned response of capuchin monkeys (

Indexed as

cannabidiol (CBD)learningmemoryMK-801monkeyprepulse inhibition

Identifiers

PMID28289391
PMCPMC5326751
OpenAlexW2591217409

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.