ArticleThe Kobe journal of medical sciences2017
Meaning and Limitation of Cortical Bone Width Measurement with DentaScan in Medication-Related Osteonecrosis of the Jaws.
Article in The Kobe journal of medical sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Early imaging signs of the use of antiresorptive medication and MRONJ: a systematic review.Clinical oral investigations · 2020Pooled it
- Black bone MRI morphometry for mandibular cortical bone measurement in head and neck cancer patients: prospective method comparison with CT.Oral surgery, oral medicine, oral pathology and oral radiology · 2026Article
- Osteonecrosis of the jaw: a rare but possible side effect in thyroid cancer patients treated with tyrosine-kinase inhibitors and bisphosphonates.Journal of endocrinological investigation · 2021Review
- Review of Myeloma Therapies and Their Potential for Oral and Maxillofacial Side Effects.Cancers · 2021Review
- Trabecular and cortical mandibular bone investigation in familial adenomatous polyposis patients.Scientific reports · 2021Article
- Several issues regarding the diagnostic imaging of medication-related osteonecrosis of the jaw.Imaging science in dentistry · 2020Review
- Tomographic study of Jaw bone changes in patients with bisphosphonate-related osteonecrosis.Journal of clinical and experimental dentistry · 2020Article
- Evaluation of mandibular cortical bone ratio on computed tomography images in patients taking bisphosphonates.Maxillofacial plastic and reconstructive surgery · 2018Article
- Detecting the earliest radiological signs of bisphosphonate-related osteonecrosis.British dental journal · 2018Review
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Authors and funding
7 authors.
Funding
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Abstract
Mandibular cortical bone measurement with x-ray imaging is known to be a potentially useful tool in the detection of dimensional changes caused by bisphosphonate. The primary purpose of this study was to assess the meaning and limitation of cortical bone measurement with computed tomography (CT) in patients with medication-related osteonecrosis of the jaw (MRONJ). The investigators obtained DentaScan images of the mandible from 15 patients with MRONJ, 15 patients with a history of antiresorptive agent administration without symptoms of MRONJ (non-MRONJ), and 15 control subjects. The cortical bone width measured on DentaScan images was compared between the three groups (ANOVA and Tukey's test). Interobserver reliability between two observers was also assessed. The values of interclass correlation coefficient were 0.48 in the MRONJ group, 0.29 in the Non-MRONJ group, and 0.34 in control group. The cortical bone widths calculated both by observer 1 and observer 2 were thicker in patients with MRONJ than in the non-MRONJ group and controls. There were significant differences in cortical bone width among the MRONJ, non-MRONJ, and control groups in observer 1 (P < 0.001) and observer 2 (P < 0.001), specifically comparing the MRONJ group with the non-MRONJ group and the control group. Cortical bone width measurement is useful for the distinction between medication-related osteonecrosis of the jaw and normal bone, in spite of the low interobserver reliability.
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