Evidence map›Paper›PMID 28289246›Full record

ReviewCold Spring Harbor perspectives in medicine2018

The Heart and Great Vessels.

Ekene Onwuka, Nakesha King, Eric Heuer, Christopher Breuer

Abstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ekene OnwukaTissue Engineering and Surgical Research, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio 43205.
Nakesha KingTissue Engineering and Surgical Research, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio 43205.
Eric HeuerTissue Engineering and Surgical Research, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio 43205.
Christopher BreuerTissue Engineering and Surgical Research, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio 43205.

Funding

Improving Tissue Engineered Vascular Graft Performance via Computational ModelingR01HL139796 · NHLBI · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI BREUER, CHRISTOPHER KANE, HUMPHREY, JAY D. · 2018 to 2025
$6.4M
Mechanisms of Vascular Neotissue Formation In Tissue Engineered Vascular GraftsR01HL098228 · NHLBI · YALE UNIVERSITY · PI BREUER, CHRISTOPHER KANE · 2010 to 2018
$3.6M
Advanced Research Training in Immunology for Surgery Trainees (ARTIST)T32AI106704 · NIAID · OHIO STATE UNIVERSITY · PI GINNY L BUMGARDNER, Jon R Wisler · 2014 to 2026
$3.5M
Development of an Improved Vascular Graft for Use in Congenital Heart SurgeryR01HL128847 · NHLBI · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI BREUER, CHRISTOPHER KANE · 2016 to 2019
$2.8M
NHLBI NIH HHS R01 HL098228NHLBI NIH HHS R01 HL128847NHLBI NIH HHS R01 HL139796NIAID NIH HHS T32 AI106704
6 · The paper itself

Abstract

Cardiovascular disease is the leading cause of mortality worldwide. We have made large strides over the past few decades in management, but definitive therapeutic options to address this health-care burden are still limited. Given the ever-increasing need, much effort has been spent creating engineered tissue to replaced diseased tissue. This article gives a general overview of this work as it pertains to the development of great vessels, myocardium, and heart valves. In each area, we focus on currently studied methods, limitations, and areas for future study.

Indexed as

Bioartificial OrgansAnimalsBiocompatible MaterialsBlood VesselsCardiovascular DiseasesHumansMyocardiumTissue EngineeringBiocompatible Materials

Identifiers

PMID28289246
PMCPMC5811399

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.