Evidence map›Paper›PMID 28289197›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Toll pathway is required for wound-induced expression of barrier repair genes in the

Amalia Capilla, Dmitry Karachentsev, Rachel A Patterson, Anita Hermann, Michelle T Juarez, William McGinnis

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Article
  3. Distinct roles of theCurrent research in insect science · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Immunological Roles ofInternational journal of molecular sciences · 2022
    Article
  10. Article
  11. Article
  12. Cells · 2022
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Acute exposure of Nicotine duringmicroPublication biology · 2021
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Amalia CapillaDivision of Biological Sciences, University of California San Diego, La Jolla, CA 92093.
Dmitry KarachentsevDivision of Biological Sciences, University of California San Diego, La Jolla, CA 92093.
Rachel A PattersonDivision of Biological Sciences, University of California San Diego, La Jolla, CA 92093.
Anita HermannDivision of Biological Sciences, University of California San Diego, La Jolla, CA 92093.
Michelle T JuarezSophie Davis School Program of Biomedical Education, City University of New York School of Medicine, City College of New York, New York, NY 10031.
William McGinnisDivision of Biological Sciences, University of California San Diego, La Jolla, CA 92093; billmcginnis.ucsd@gmail.com.
University of California, San Diego · USCity University of New York · US

Funding

UCSD/SDSU IRACDAK12GM068524 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI TREJO, JOANN · 2003 to 2025
$24.4M
Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Cellular/Molecular Basis of Development: Research CenterG12MD007603 · NIMHD · CITY COLLEGE OF NEW YORK · PI PEZZANO, MARK · 2012 to 2017
$11.5M
SPECIFICITY IN HOMEOTIC RESPONSE ELEMENTSR01HD028315 · NICHD · YALE UNIVERSITY · PI MCGINNIS, WILLIAM JAMES · 1991 to 2005
$2.5M
Conversion of DNA nuclease activation during both damage and infectionR03AI117671 · NIAID · CITY COLLEGE OF NEW YORK · PI JUAREZ, MICHELLE TATOM · 2015 to 2016
$156k
NIAID NIH HHS R03 AI117671NICHD NIH HHS R01 HD028315NIGMS NIH HHS K12 GM068524NIH HHS P40 OD018537NIMHD NIH HHS G12 MD007603
6 · The paper itself

Abstract

The epidermis serves as a protective barrier in animals. After epidermal injury, barrier repair requires activation of many wound response genes in epidermal cells surrounding wound sites. Two such genes in

Indexed as

AnimalsDrosophila melanogasterDrosophila ProteinsGene Expression RegulationModels, BiologicalNF-kappa BSignal TransductionToll-Like ReceptorsWound HealingDrosophila ProteinsNF-kappa BToll-Like ReceptorsDrosophilaepidermal TollNF-κBSpätzlewound repair

Identifiers

PMID28289197
PMCPMC5380074
OpenAlexW2597223890

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.