Evidence map›Paper›PMID 28289183›Full record

ArticleJournal of the American Society of Nephrology : JASN2017

C1-Inhibitor Decreases the Release of Vasculitis-Like Chemotactic Endothelial Microvesicles.

Maria Mossberg, Anne-Lie Ståhl, Robin Kahn, Ann-Charlotte Kristoffersson, Ramesh Tati, Caroline Heijl, Mårten Segelmark, L M Fredrik Leeb-Lundberg, Diana Karpman

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 36 citations in OpenAlex.

  1. The role of extracellular vesicles in kidney disease progression.Kidney research and clinical practice · 2026
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  14. Kinin B1 Receptor Is Important in the Pathogenesis of Myeloperoxidase-Specific ANCA GN.Journal of the American Society of Nephrology : JASN · 2020
    Article
  15. Article
  16. Review
  17. Review
  18. New insight into the role of extracellular vesicles in kidney disease.Journal of cellular and molecular medicine · 2019
    Review
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  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Maria MossbergDepartments of Pediatrics and.
Anne-Lie StåhlDepartments of Pediatrics and.
Robin KahnDepartments of Pediatrics and.
Ann-Charlotte KristofferssonDepartments of Pediatrics and.
Ramesh TatiDepartments of Pediatrics and.
Caroline HeijlNephrology, Clinical Sciences Lund, and.
Mårten SegelmarkDepartment of Medical and Health Sciences, Linköping University, Linköping, Sweden.
L M Fredrik Leeb-LundbergUnit of Drug Target Discovery, Division of Pharmacology and Structural Biology, Department of Experimental Medical Science, Lund University, Lund, Sweden; and.
Diana KarpmanDepartments of Pediatrics and diana.karpman@med.lu.se.
Pediatrics and Genetics · USLund University · SELinköping University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The kinin system is activated during vasculitis and may contribute to chronic inflammation. C1-inhibitor is the main inhibitor of the kinin system. In this study, we investigated the presence of the kinin B1 receptor on endothelial microvesicles and its contribution to the inflammatory process. Compared with controls (

Indexed as

AdolescentAdultAgedAged, 80 and overCell-Derived MicroparticlesChemotaxisChildComplement C1 Inactivator ProteinsComplement C1 Inhibitor ProteinEndothelium, VascularFemaleHumansMaleMiddle AgedVasculitisYoung AdultComplement C1 Inactivator ProteinsComplement C1 Inhibitor ProteinSERPING1 protein, humanChronic inflammationcomplementglomerular endothelial cellskininneutrophilsvasculitis

Identifiers

PMID28289183
PMCPMC5533224
OpenAlexW2595581741

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.