Evidence map›Paper›PMID 28289136›Full record

ArticleDevelopment (Cambridge, England)2017

Estrogen modulates mesenchyme-epidermis interactions in the adult nipple.

Hsing-Jung Wu, Ji Won Oh, Dan F Spandau, Sunil Tholpady, Jesus Diaz, Laura J Schroeder, Carlos D Offutt, Adam B Glick, Maksim V Plikus, Sachiko Koyama and 1 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Development (Cambridge, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Hsing-Jung WuMedical Sciences Program, Indiana University School of Medicine, Bloomington, IN 47405, USA.
Ji Won OhDepartment of Developmental and Cell Biology, Sue and Bill Gross Stem Cell Research Center, Center for Complex Biological Systems, University of California Irvine, Irvine, CA 92697, USA.
Dan F SpandauDepartment of Dermatology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Sunil TholpadyDepartment of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Jesus DiazMedical Sciences Program, Indiana University School of Medicine, Bloomington, IN 47405, USA.
Laura J SchroederMedical Sciences Program, Indiana University School of Medicine, Bloomington, IN 47405, USA.
Carlos D OffuttMedical Sciences Program, Indiana University School of Medicine, Bloomington, IN 47405, USA.
Adam B GlickDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
Maksim V PlikusDepartment of Developmental and Cell Biology, Sue and Bill Gross Stem Cell Research Center, Center for Complex Biological Systems, University of California Irvine, Irvine, CA 92697, USA.
Sachiko KoyamaMedical Sciences Program, Indiana University School of Medicine, Bloomington, IN 47405, USA.
John FoleyMedical Sciences Program, Indiana University School of Medicine, Bloomington, IN 47405, USA jgfoley@indiana.edu.ORCID 0000-0003-0266-8488
Indiana University Bloomington · USIndiana University School of MedicineUniversity of California, Irvine · USPennsylvania State University · US

Funding

Induction of fat regeneration in skin wounds by hair follicle signalingR01AR067273 · NIAMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI PLIKUS, MAKSIM V · 2014 to 2018
$1.9M
Skin Defense by Dermal AdipocytesR01AR069653 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GALLO, RICHARD L · 2016 to 2020
$1.9M
NIAMS NIH HHS R01 AR067273NIAMS NIH HHS R01 AR069653
6 · The paper itself

Abstract

Maintenance of specialized epidermis requires signals from the underlying mesenchyme; however, the specific pathways involved remain to be identified. By recombining cells from the ventral skin of the

Indexed as

Epidermal CellsAgingAnimalsBiomarkersCell CommunicationCellular ReprogrammingCollagenComputational BiologyDermisDown-RegulationEstrogensFemaleFibroblastsGene Expression Regulation, DevelopmentalKeratinocytesMesodermBiomarkersCollagenEstrogensReceptor, Platelet-Derived Growth Factor alphaReceptors, EstrogenRNA, MessengerTransforming Growth Factor betaEpidermisEstrogen receptor αFibroblastNippleTGFβ

Identifiers

PMID28289136
PMCPMC5399661
OpenAlexW2595827209

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.