Evidence map›Paper›PMID 28289079›Full record

ArticleEMBO molecular medicine2017

Deletion of

Kyle G Potts, Chad R Irwin, Nicole A Favis, Desmond B Pink, Krista M Vincent, John D Lewis, Ronald B Moore, Mary M Hitt, David H Evans

Open access · goldAbstract read
In one paragraph

Article in EMBO molecular medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 48 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Kyle G PottsDepartment of Oncology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
Chad R IrwinLi Ka Shing Institute of Virology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
Nicole A FavisLi Ka Shing Institute of Virology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
Desmond B PinkDepartment of Oncology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
Krista M VincentDepartment of Oncology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
John D LewisDepartment of Oncology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.ORCID 0000-0002-7734-1204
Ronald B MooreDepartment of Oncology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
Mary M HittDepartment of Oncology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
David H EvansLi Ka Shing Institute of Virology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada devans@ualberta.ca.ORCID 0000-0001-5871-299X
University of Alberta · CAWestern University · CA

Funding

CIHR BOG 25964CIHR MOP 130473
6 · The paper itself

Abstract

Bladder cancer has a recurrence rate of up to 80% and many patients require multiple treatments that often fail, eventually leading to disease progression. In particular, standard of care for high-grade disease, Bacillus Calmette-Guérin (BCG), fails in 30% of patients. We have generated a novel oncolytic vaccinia virus (VACV) by mutating the

Indexed as

Gene DeletionAnimalsCell Line, TumorFemaleHumansImmunityMice, Inbred BALB CMice, NudeOncolytic VirotherapyOncolytic VirusesRatsRibonucleotide ReductasesTumor Cells, CulturedUrinary BladderUrinary Bladder NeoplasmsVaccinia virusRibonucleotide ReductasesViral Proteinsbladder cancerimmunotherapyoncolytic virusribonucleotide reductasevaccinia virus

Identifiers

PMID28289079
PMCPMC5412795
OpenAlexW2597132924

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.