SynthesisBMJ open2017
Paediatric early warning systems for detecting and responding to clinical deterioration in children: a systematic review.
Synthesis in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04876872 (The Effectiveness of Modified Pediatric Early Warning Score and Pediatric Hospitalization Risk Scoring II in Patients Applying to the Pediatric Emergency Unit During Pandemic Period Associated With COVID-19 Disease), which is not on this map. Cited by 86 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effectiveness of Modified Pediatric Early Warning Score and Pediatric Hospitalization Risk Scoring II in Patients Applying to the Pediatric Emergency Unit During Pandemic Period Associated With COVID-19 Disease
Who cites it
86 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- 2025 Korean Guidelines for Cardiopulmonary Resuscitation: Part 7. Pediatric basic life support.Clinical and experimental emergency medicine · 2026Guideline
- Mortality predictors in pediatric emergency department presentations: a systematic review and meta-analysis.BMC emergency medicine · 2025Pooled it
- Pooled it
- Physiological track-and-trigger/early warning systems for use in maternity care.The Cochrane database of systematic reviews · 2021Pooled it
- Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children.Intensive care medicine · 2020Guideline
- Optimising paediatric afferent component early warning systems: a hermeneutic systematic literature review and model development.BMJ open · 2019Pooled it
- Pooled it
- Technical Approaches to Predicting Acute Deterioration in Pediatric Inpatients: Protocol for a Scoping Review.JMIR research protocols · 2026Article
- Evaluating the Scale-Up and Sustainability of the Paediatric ESCALATION System in Country Western Australia: A Multi-Methods Study.The Australian journal of rural health · 2026Article
- Paediatric Practitioners' Acceptance of the National Paediatric Early Warning System (PEWS).Nursing in critical care · 2026Article
- Performance of the Dutch Pediatric Early Warning Score: a nationwide study in academic, large teaching and general hospital contexts, using real-world data.BMJ paediatrics open · 2026Article
- Performance of PRISM III and pediatric early warning score for predicting patients needing increased level of care in a pediatric intermediate care unit.European journal of pediatrics · 2026Observational
- From scores to signals: evolution and innovations in pediatric early warning systems.Acute and critical care · 2026Article
- Prognostic performance and clinical utility of a modified Brighton pediatric early warning score for 24-h ICU admission in a resource-limited pediatric emergency department.European journal of pediatrics · 2026Article
- Parent's Process of Escalation of Care for Their Deteriorating Children Admitted to Paediatric Wards: A Grounded Theory.Journal of clinical nursing · 2026Article
- Vital signs as biomarkers of early clinical deterioration in pediatric emergency departments: physiology, interpretation, and innovations: a narrative review.International journal of emergency medicine · 2026Review
- The Role of Pediatric Early Warning Scores (PEWS) in Determining PICU Transfer Necessity and Length of Stay.Medical journal of the Islamic Republic of Iran · 2026Article
- Effect of a Pediatric Early Warning System Educational Program on Nurses' Capacity to Detect Clinical Deterioration: A Quasi-Experimental Study.Journal of nursing management · 2026Article
- Signal detection for pediatric patient deterioration with nursing students: An explanatory sequential design mixed-methods study.International journal of nursing studies advances · 2025Article
- Pediatric Early Warning System (PEWS) Association with ICU Mortality in Children with Acute Lymphoblastic Leukemia: A Cohort Study from Kazakhstan.Medicina (Kaunas, Lithuania) · 2025Article
26 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo systematically review the available evidence on paediatric early warning systems (PEWS) for use in acute paediatric healthcare settings for the detection of, and timely response to, clinical deterioration in children.
methodThe electronic databases PubMed, MEDLINE, CINAHL, EMBASE and Cochrane were searched systematically from inception up to August 2016. Eligible studies had to refer to PEWS, inclusive of rapid response systems and teams. Outcomes had to be specific to the identification of and/or response to clinical deterioration in children (including neonates) in paediatric hospital settings (including emergency departments). 2 review authors independently completed the screening and selection process, the quality appraisal of the retrieved evidence and data extraction; with a third reviewer resolving any discrepancies, as required. Results were narratively synthesised.
resultsFrom a total screening of 2742 papers, 90 papers, of varied designs, were identified as eligible for inclusion in the review. Findings revealed that PEWS are extensively used internationally in paediatric inpatient hospital settings. However, robust empirical evidence on which PEWS is most effective was limited. The studies examined did however highlight some evidence of positive directional trends in improving clinical and process-based outcomes for clinically deteriorating children. Favourable outcomes were also identified for enhanced multidisciplinary team work, communication and confidence in recognising, reporting and making decisions about child clinical deterioration.
conclusionsDespite many studies reporting on the complexity and multifaceted nature of PEWS, no evidence was sourced which examined PEWS as a complex healthcare intervention. Future research needs to investigate PEWS as a complex multifaceted sociotechnical system that is embedded in a wider safety culture influenced by many organisational and human factors. PEWS should be embraced as a part of a larger multifaceted safety framework that will develop and grow over time with strong governance and leadership, targeted training, ongoing support and continuous improvement.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.