ArticleThe British journal of general practice : the journal of the Royal College of General Practitioners2017
Prescription rates of adrenaline auto-injectors for children in UK general practice: a retrospective cohort study.
Article in The British journal of general practice : the journal of the Royal College of General Practitioners, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 28 citations in OpenAlex.
- Health inequities in pediatric anaphylaxis: A policy framework and call to action for equitable care from SIAIP allergy prevention commission.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026Review
- Nationwide epinephrine auto-injector dispensing in Greece: a drug-utilization study providing insights into anaphylaxis epidemiology and emergency-treatment preparedness.Frontiers in allergy · 2026Article
- Adrenaline Auto-Injector Prescribing in Primary Care in England: An Analysis of Non-Standard Dosing.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2026Article
- Adrenaline Auto-Injectors for Preventing Fatal Anaphylaxis.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2025Review
- Investigating awareness and implementation of adrenaline auto-injectors (AAI) via the 'Spare Pens in Schools' scheme in Wales: a cross-sectional pilot study.BMJ paediatrics open · 2024Article
- Anaphylaxis in Omani Patients: A Study from a Tertiary Care Center.Oman medical journal · 2022Article
- Review
- Accidental adrenaline auto-injector-induced digital ischaemia: a proposed treatment algorithm.BMJ case reports · 2021Article
- EAACI Task force Clinical epidemiology of anaphylaxis: experts' perspective on the use of adrenaline autoinjectors in Europe.Clinical and translational allergy · 2020Article
- Common causes of emergency department visits for anaphylaxis in Korean community hospitals: A cross-sectional study.Medicine · 2019Article
- Anaphylaxis triggers in a large tertiary care hospital in Qatar: a retrospective study.The World Allergy Organization journal · 2018Article
- Adrenaline auto-injector prescribing may be putting patients at risk.The British journal of general practice : the journal of the Royal College of General Practitioners · 2017Article
- A national survey of Russian physicians' knowledge of diagnosis and management of food-induced anaphylaxis.BMJ open · 2017Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
backgroundAdrenaline auto-injectors (AAI) should be provided to individuals considered to be at high risk of anaphylaxis. There is some evidence that the rate of AAI prescription is increasing, but the true extent has not been previously quantified.
aimTo estimate the trends in annual GP-issued prescriptions for AAI among UK children between 2000 and 2012. DESIGN AND
settingRetrospective cohort study using data from primary care practices that contributed to The Health Improvement Network (THIN) database.
methodChildren and young people aged between 0-17 years of age with a prescription for AAIs were identified, and annual AAI device prescription rates were estimated using Stata (version 12).
resultsA total of 1.06 million UK children were identified, providing 5.1 million person years of follow-up data. Overall, 23 837 children were deemed high risk by their GPs, and were prescribed 98 737 AAI devices. This equates to 4.67 children (95% confidence interval [CI] = 4.66 to 4.69), and 19.4 (95% CI = 19.2 to 19.5) devices per 1000 person years. Between 2000 and 2012, there has been a 355% increase in the number of children prescribed devices, and a 506% increase in the total number of AAI devices prescribed per 1000 person years in the UK. The number of devices issued per high-risk child during this period has also increased by 33%.
conclusionThe number of children being prescribed AAI devices and the number of devices being prescribed in UK primary care between 2000 and 2012 has significantly increased. A discussion to promote rational prescribing of AAIs in the NHS is needed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.