Evidence map›Paper›PMID 28289010›Full record

ArticleCirculation2017

Response by Methawasin and Granzier to Letter Regarding Article, "Experimentally Increasing the Compliance of Titin Through RNA Binding Motif-20 (RBM20) Inhibition Improves Diastolic Function in a Mouse Model of Heart Failure With Preserved Ejection Fraction".

Mei Methawasin, Henk Granzier

Abstract readLetterComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Circulation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Mei MethawasinFrom Department of Cellular and Molecular Medicine, College of Medicine, University of Arizona, Tucson.
Henk GranzierFrom Department of Cellular and Molecular Medicine, College of Medicine, University of Arizona, Tucson.

Funding

Function of Giant Sarcomere Matrix Proteins in MuscleR01HL062881 · NHLBI · WASHINGTON STATE UNIVERSITY · PI GRANZIER, HENK L. · 1999 to 2018
$6.4M
TITIN AND HEART FUNCTION AND DISEASE (INDIVIDUAL)R01HL061497 · NHLBI · WASHINGTON STATE UNIVERSITY · PI GRANZIER, HENK L. · 1998 to 2007
$3.3M
Myofilament-based mechanisms of diastolic dysfunction in HFpEFR01HL118524 · NHLBI · UNIVERSITY OF ARIZONA · PI GRANZIER, HENK L., LEWINTER, MARTIN M · 2014 to 2017
$2.5M
Titin-Based Adaptations of Cardiac FunctionR01HL115988 · NHLBI · UNIVERSITY OF ARIZONA · PI GRANZIER, HENK L. · 2013 to 2019
$2.3M
Role of the Giant Protein Titin in Skeletal Muscle Structure and FunctionR01AR060697 · NIAMS · UNIVERSITY OF ARIZONA · PI GRANZIER, HENK L. · 2011 to 2015
$1.7M
NHLBI NIH HHS R01 HL061497NHLBI NIH HHS R01 HL062881NHLBI NIH HHS R01 HL115988NHLBI NIH HHS R01 HL118524NIAMS NIH HHS R01 AR060697
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ConnectinStroke VolumeAnimalsDiastoleHeart FailureMiceRNA-Binding MotifsRNA-Binding ProteinsConnectinRBM20 protein, mouseRNA-Binding Proteins

Identifiers

PMID28289010
PMCPMC5401660

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.