ArticleBMC pediatrics2017
Laparoscopic resection of neuroblastomas in low- to high-risk patients without image-defined risk factors is safe and feasible.
Article in BMC pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- How well do image-defined risk factors (IDRFs) predict surgical outcomes and survival in patients with neuroblastoma? A systematic review and meta-analysis.Pediatric surgery international · 2020Pooled it
- Robot-assisted versus conventional minimally invasive surgery in the treatment of paediatric neuroblastoma: a single-centre retrospective study.Pediatric surgery international · 2026Article
- International Society of Paediatric Surgical Oncology (IPSO) Minimally Invasive Surgery (MIS) Guidelines.Ecancermedicalscience · 2026Article
- Minimally invasive surgery in neurogenic tumours.Ecancermedicalscience · 2025Review
- Combined Laparoscopic and Posterior Approach Resection of Presacral Neuroblastoma with Rectobulbar Urethral Fistula.Surgical case reports · 2025Article
- Beyond image defined risk factors (IDRFs): a delphi survey highlighting definition of the surgical complexity index (SCI) in neuroblastoma.Pediatric surgery international · 2023Article
- High-Risk Neuroblastoma: A Surgical Perspective.Children (Basel, Switzerland) · 2023Review
- Feasibility and safety of laparoscopic tumor resection in children with abdominal neuroblastomas.Pediatric surgery international · 2023Article
- Association of Image-Defined Risk Factors with Clinical, Biological Features and Outcome in Neuroblastoma.Children (Basel, Switzerland) · 2022Article
- Laparoscopic approach for abdominal neuroblastoma in Japan: results from nationwide multicenter survey.Surgical endoscopy · 2022Article
- COPediatric surgery international · 2022Article
- International Society of Paediatric Surgical Oncology (IPSO) Surgical Practice Guidelines.Ecancermedicalscience · 2022Article
- Two-stage laparoscopic resection of giant hepatoblastoma in infants combined with liver partial partition and artery ligation.World journal of surgical oncology · 2021Article
- Association between image-defined risk factors and neuroblastoma outcomes.Journal of pediatric surgery · 2019Article
- Neuroblastoma: Tumor Biology and Its Implications for Staging and Treatment.Children (Basel, Switzerland) · 2019Review
- Advances in the Surgical Treatment of Neuroblastoma.Chinese medical journal · 2018Review
- Transperitoneal Laparoscopic Adrenalectomy in Children - Initial Experience in an Emerging Tertiary Center in Eastern India.Journal of Indian Association of Pediatric SurgeonsArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSeveral studies have reported that minimally invasive surgery (MIS) might be considered for resecting neuroblastomas without image-defined risk factors (IDRFs); however, there are no studies comparing the outcomes of laparotomy and laparoscopy in IDRF-negative patients. Thus, we investigated the feasibility of laparoscopic surgery and compared the two abovementioned approaches.
methodsTo compare the effects of laparotomy with those of laparoscopy in patients with neuroblastomas without IDRFs, the following items were retrospectively compared: largest tumor dimension, volume of blood loss, time required to initiate postoperative feeding, locoregional recurrence rate, survival, etc.
resultsNine patients without IDRFs (three at low-to-medium risk and six at high risk) underwent laparotomy, and seven patients without IDRFs (two at low-to-medium risk and five at high risk) underwent laparoscopy. Median duration of surgery was 221 (130-304) and 172 (122-253) min in the laparotomy and laparoscopy groups, respectively, showing no significant difference. Median postoperative time required for resuming meal consumption was significantly longer in the laparotomy (4 days; 2-5) group than that in the laparoscopy group (3 days; 2-3; p = 0.023). Median blood loss was significantly higher in the laparotomy group (5 ml/Kg;2.6-16) than that in the laparoscopy group (2.1 ml/Kg;0.1-4.0; P = 0.037). Median follow-up period was 81 (52-94) and 21 (17-28) months, locoregional recurrence rates were 22 and 0% at 1 year, 1-year progression-free survival rates were 78 and 100%, and overall survival rates were 67 and 100% in the laparotomy and laparoscopy groups, respectively, with no significant differences.
conclusionsMIS for the treatment of neuroblastomas without IDRFs in low- to high-risk patients is safe and feasible and does not compromise the treatment outcome.
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