Evidence map›Paper›PMID 28288586›Full record

ArticleBMC cardiovascular disorders2017

Gender differences in all-cause, cardiovascular and cancer mortality during long-term follow-up after acute myocardial infarction; a prospective cohort study.

Kristin Marie Kvakkestad, Morten Wang Fagerland, Jan Eritsland, Sigrun Halvorsen

Open access · goldAbstract read
In one paragraph

Article in BMC cardiovascular disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
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  12. All-Cause and Cancer Mortality Trends in Macheng, China (1984⁻2013): An Age-Period-Cohort Analysis.International journal of environmental research and public health · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Kristin Marie KvakkestadDepartment of Cardiology, Oslo University Hospital Ulleval, Postboks 4950 Nydalen, 0424, Oslo, Norway.
Morten Wang FagerlandOslo Centre for Biostatistics and Epidemiology, Research Support Services, Postboks 1110 Blindern, 0317, Oslo, Norway.
Jan EritslandDepartment of Cardiology, Oslo University Hospital Ulleval, Postboks 4950 Nydalen, 0424, Oslo, Norway.
Sigrun HalvorsenDepartment of Cardiology, Oslo University Hospital Ulleval, Postboks 4950 Nydalen, 0424, Oslo, Norway. sigrun.h@online.no.
University of Oslo · NOOslo University Hospital · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGender differences in short-term mortality in acute myocardial infarction (AMI) have been studied extensively, whereas gender differences in long-term mortality and cause of death largely remain unknown. The aim of this study was to assess the long-term risk of all-cause, cardiovascular and cancer death after AMI in women compared to men.

methodsConsecutive AMI patients were enrolled in a prospective registry between 2005 and 2011. Date and cause of death were obtained by linkage with the Norwegian Cause of Death Registry, with censoring date 31 December 2012. AMI patients with ST-segment elevation (STEMI, n = 5159) and without (NSTEMI, n = 4899) were analysed separately.

resultsThe 5-years all-cause mortality rates in STEMI were 29% in women vs. 17% in men, and 42% vs. 29% in NSTEMI, respectively. After adjustment for age and other confounders, women with STEMI had similar (HR 1.13 [95% CI: 0.98-1.32]) and women with NSTEMI lower (HR 0.82 [95% CI: 0.73-0.92]) risk of long-term all-cause mortality compared to men. Competing-risks analysis showed no significant gender differences in age-adjusted risk of cardiovascular death nor of cancer death. In both genders, the annual risk of cardiovascular death was low after 1 year, but exceeded annual risk of cancer death throughout follow-up.

conclusionDuring long-term follow-up, women with STEMI had similar and women with NSTEMI lower adjusted risk of all-cause mortality compared to men. Age-adjusted risk of death due to cardiovascular disease was similar in both genders and higher than risk of death due to cancer throughout the follow-up period.

Indexed as

RegistriesRisk AssessmentAgedAged, 80 and overCause of DeathFemaleFollow-Up StudiesHospital MortalityHumansMaleMiddle AgedMyocardial InfarctionNeoplasmsNorwayProspective StudiesRisk FactorsCancer mortalityCardiovascular mortalityGenderMyocardial infarctionWomen

Identifiers

PMID28288586
PMCPMC5348805
OpenAlexW2597404100

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.