ReviewCurrent opinion in neurobiology2017
Sleep regulation of the distribution of cortical firing rates.
Review in Current opinion in neurobiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
42 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Can REM Sleep Localize the Epileptogenic Zone? A Systematic Review and Analysis.Frontiers in neurology · 2020Pooled it
- Neuronal spiking in the mammalian forebrain is dominated by a heterogeneous ground state.Neuron · 2026Article
- Preoptic area influences sleep-related seizures in a genetic epilepsy mouse model.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Article
- Article
- A nonoscillatory, millisecond-scale embedding of brain state provides insight into behavior.Nature neuroscience · 2024Article
- Article
- Linking activity dyshomeostasis and sleep disturbances in Alzheimer disease.Nature reviews. Neuroscience · 2024Review
- Wake slow waves in focal human epilepsy impact network activity and cognition.Nature communications · 2023Article
- A non-oscillatory, millisecond-scale embedding of brain state provides insight into behavior.bioRxiv : the preprint server for biology · 2023Article
- Fast-local and slow-global neural ensembles in the mouse brain.Network neuroscience (Cambridge, Mass.) · 2023Article
- Sleep slow-wave oscillations trigger seizures in a genetic epilepsy model of Dravet syndrome.Brain communications · 2023Article
- Psilocin acutely alters sleep-wake architecture and cortical brain activity in laboratory mice.Translational psychiatry · 2022Article
- Disrupted neural correlates of anesthesia and sleep reveal early circuit dysfunctions in Alzheimer models.Cell reports · 2022Article
- Editorial:Frontiers in neuroscience · 2022Article
- Artificial sleep-like up/down-states induce synaptic plasticity in cortical neurons from mouse brain slices.Frontiers in cellular neuroscience · 2022Article
- Brain neural patterns and the memory function of sleep.Science (New York, N.Y.) · 2021Review
- Acetylcholine-gated current translates wake neuronal firing rate information into a spike timing-based code in Non-REM sleep, stabilizing neural network dynamics during memory consolidation.PLoS computational biology · 2021Article
- Article
- Thalamo-cortical spiking model of incremental learning combining perception, context and NREM-sleep.PLoS computational biology · 2021Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Sleep is thought to mediate both mnemonic and homeostatic functions. However, the mechanism by which this brain state can simultaneously implement the 'selective' plasticity needed to consolidate novel memory traces and the 'general' plasticity necessary to maintain a well-functioning neuronal system is unclear. Recent findings show that both of these functions differentially affect neurons based on their intrinsic firing rate, a ubiquitous neuronal heterogeneity. Furthermore, they are both implemented by the NREM slow oscillation, which also distinguishes neurons based on firing rate during sequential activity at the DOWN→UP transition. These findings suggest a mechanism by which spiking activity during the slow oscillation acts to maintain network statistics that promote a skewed distribution of neuronal firing rates, and perturbation of that activity by hippocampal replay acts to integrate new memory traces into the existing cortical network.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.