Evidence map›Paper›PMID 28288347›Full record

ArticleBiomaterials2017

Exploration of the metal coordination region of concanavalin A for its interaction with human norovirus.

Duwoon Kim, Hee-Min Lee, Kyung-Seo Oh, Ah Young Ki, Rachael A Protzman, Dongkyun Kim, Jong-Soon Choi, Min Ji Kim, Sung Hyun Kim, Bipin Vaidya and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomaterials, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. A Survey of Analytical Techniques for Noroviruses.Foods (Basel, Switzerland) · 2020
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Duwoon KimDepartment of Food Science and Technology and Foodborne Virus Research Center, Chonnam National University, Gwangju 61186, Republic of Korea; Bioenergy Research Center, Chonnam National University, Gwangju 61186, South Korea.
Hee-Min LeeDepartment of Food Science and Technology and Foodborne Virus Research Center, Chonnam National University, Gwangju 61186, Republic of Korea; Biological Disaster Analysis Group, Korea Basic Science Institute, Gwahak-ro, Yuseong-gu, Daejeon 34133, Republic of Korea.
Kyung-Seo OhDepartment of Food Science and Technology and Foodborne Virus Research Center, Chonnam National University, Gwangju 61186, Republic of Korea; Biological Disaster Analysis Group, Korea Basic Science Institute, Gwahak-ro, Yuseong-gu, Daejeon 34133, Republic of Korea.
Ah Young KiBiological Disaster Analysis Group, Korea Basic Science Institute, Gwahak-ro, Yuseong-gu, Daejeon 34133, Republic of Korea; Graduate School of Analytical Science and Technology, Chungnam National University, Daejeon, Republic of Korea.
Rachael A ProtzmanDepartment of Food Science and Technology and Foodborne Virus Research Center, Chonnam National University, Gwangju 61186, Republic of Korea.
Dongkyun KimBiological Disaster Analysis Group, Korea Basic Science Institute, Gwahak-ro, Yuseong-gu, Daejeon 34133, Republic of Korea.
Jong-Soon ChoiBiological Disaster Analysis Group, Korea Basic Science Institute, Gwahak-ro, Yuseong-gu, Daejeon 34133, Republic of Korea; Graduate School of Analytical Science and Technology, Chungnam National University, Daejeon, Republic of Korea.
Min Ji KimMicrobiology Division, Health and Environment Research Institute of Gwangju, Gwangju 61986, Republic of Korea.
Sung Hyun KimHygienic Safety and Analysis Center, World Institute of Kimchi, Gwangju 61755, Republic of Korea.
Bipin VaidyaDepartment of Food Science and Technology and Foodborne Virus Research Center, Chonnam National University, Gwangju 61186, Republic of Korea; Bioenergy Research Center, Chonnam National University, Gwangju 61186, South Korea.
Seung Jae LeeDepartment of Chemistry and Research Center for Physics and Chemistry, Chonbuk National University, Jeonju 54896, Republic of Korea. Electronic address: slee026@jbnu.ac.kr.
Joseph KwonBiological Disaster Analysis Group, Korea Basic Science Institute, Gwahak-ro, Yuseong-gu, Daejeon 34133, Republic of Korea. Electronic address: joseph@kbsi.re.kr.
Korea Basic Science Institute · KRChonnam National University · KRGwangju Health University · KRJeonbuk National University · KRWorld Institute of Kimchi · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rapid methods for the detection and clinical treatment of human norovirus (HuNoV) are needed to control foodborne disease outbreaks, but reliable techniques that are fast and sensitive enough to detect small amounts of HuNoV in food and aquatic environments are not yet available. We explore the interactions between HuNoV and concanavalin A (Con A), which could facilitate the development of a sensitive detection tool for HuNoV. Biophysical studies including hydrogen/deuterium exchange (HDX) mass spectrometry and surface plasmon resonance (SPR) revealed that when the metal coordinated region of Con A, which spans Asp16 to His24, is converted to nine alanine residues (mCon A

Indexed as

Acrylic ResinsAmino Acid SequenceConcanavalin ADeuterium Exchange MeasurementFood MicrobiologyHumansMetalsMicrospheresNorovirusPhytohemagglutininsPlant LectinsSoybean ProteinsAcrylic Resinscarbopol 940Concanavalin AMetalsPhytohemagglutininsPlant Lectinssoybean lectinSoybean ProteinsConcanavalin AHuman norovirus (GI and GII)LectinMetal coordinationPolyacrylamide bead

Identifiers

PMID28288347
PMCPMC7112440
OpenAlexW2592071277

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.