Trial reportMedical care2017
An Electronic Health Record-based Intervention to Promote Hepatitis C Virus Testing Among Adults Born Between 1945 and 1965: A Cluster-randomized Trial.
Trial report in Medical care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- Electronic Health Record Nudges and Health Care Quality and Outcomes in Primary Care: A Systematic Review.JAMA network open · 2024Pooled it
- Electronic Medical Alerts Increase Screening for Chronic Hepatitis B: A Randomized, Double-Blind, Controlled Trial.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2018Trial
- Optimizing Hepatitis C Virus Antibody Testing Strategy and Setting: Results From a Large Real-World Screening Program.Open forum infectious diseases · 2026Article
- Review
- Article
- Engaging Physicians and Systems to Improve Hepatitis C Virus Testing in Baby Boomers.Healthcare (Basel, Switzerland) · 2023Article
- Using Electronic Clinical Decision Support to Examine Vision Rehabilitation Referrals and Practice Guidelines in Ophthalmology.Translational vision science & technology · 2022Article
- Birth cohort hepatitis C antibody prevalence in real-world screening settings in Ontario.Canadian liver journal · 2022Article
- Digital Health Interventions to Enhance Prevention in Primary Care: Scoping Review.JMIR medical informatics · 2022Article
- Micro-Elimination of Hepatitis C among Patients with Kidney Disease by Using Electronic Reminder System-A Hospital-Based Experience.Journal of clinical medicine · 2022Article
- Differences in inpatient and outpatient hepatitis C virus prevalence and linkage to care rates in a safety net hospital hepatitis C screening program.Journal of gastroenterology and hepatology · 2021Article
- Developing an Ophthalmology Clinical Decision Support System to Identify Patients for Low Vision Rehabilitation.Translational vision science & technology · 2021Article
- What do primary care staff know and do about blood borne virus testing and care for migrant patients? A national survey.BMC public health · 2021Article
- Patient and provider-level barriers to hepatitis C screening and linkage to care: A mixed-methods evaluation.Journal of viral hepatitis · 2020Article
- Assessing the Effectiveness of Strategies in US Birth Cohort Screening for Hepatitis C Infection.Journal of clinical and translational hepatology · 2020Review
- Electronic medical record alert activation increase hepatitis C and HIV screening rates in primary care practices within a large healthcare system.Preventive medicine reports · 2020Article
- Primary care provider perceptions and experiences of implementing hepatitis C virus birth cohort testing: a qualitative formative evaluation.BMC health services research · 2019Article
- Improving hepatitis C screening and diagnosis in patients born between 1945 and 1965 in a safety-net primary care clinic.BMJ open quality · 2019Article
- Economically Efficient Hepatitis C Virus Treatment Prioritization Improves Health Outcomes.Medical decision making : an international journal of the Society for Medical Decision Making · 2018Article
- Impact of an electronic health record alert in primary care on increasing hepatitis c screening and curative treatment for baby boomers.Hepatology (Baltimore, Md.) · 2017Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundThe Centers for Disease Control and Prevention (CDC) recommends one-time hepatitis C virus (HCV) antibody testing for "Birth Cohort" adults born during 1945-1965.
objectiveTo examine the impact of an electronic health record (EHR)-embedded best practice alert (BPA) for HCV testing among Birth Cohort adults.
designCluster-randomized trial was conducted from April 29, 2013 to March 29, 2014. SUBJECTS AND
settingTen community and hospital-based primary care practices. Participants were attending physicians and medical residents during 25,620 study-eligible visits.
interventionPhysicians in all practices received a brief introduction to the CDC testing recommendations. At visits for eligible patients at intervention sites, physicians received a BPA through the EHR to order HCV testing or medical assistants were prompted to post a testing order for the physician. Physicians in control sites did not receive the BPA. MAIN OUTCOMES: HCV testing; the incidence of HCV antibody positive tests was a secondary outcome.
resultsTesting rates were greater among Birth Cohort patients in intervention sites (20.2% vs. 1.8%, P<0.0001) and the odds of testing were greater in intervention sites after controlling for imbalances of patient and visit characteristics between comparison groups [odds ratio (OR), 9.0; 95% confidence interval, 7.6-10.7). The adjusted OR of identifying HCV antibody positive patients was also greater in intervention sites (OR, 2.1; 95% confidence interval, 1.3-11.2).
conclusionsAn EHR-embedded BPA markedly increased HCV testing among Birth Cohort patients, but the majority of eligible patients did not receive testing indicating a need for more effective methods to promote uptake.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.