Evidence map›Paper›PMID 28288074›Full record

Trial reportMedical care2017

Racial Differences and Disparities in Osteoporosis-related Bone Health: Results From the PAADRN Randomized Controlled Trial.

Peter Cram, Kenneth G Saag, Yiyue Lou, Stephanie W Edmonds, Sylvie F Hall, Douglas W Roblin, Nicole C Wright, Michael P Jones, Fredric D Wolinsky, PAADRN Investigators*

Abstract readRandomized Controlled TrialPragmatic Clinical Trial
In one paragraph

Trial report in Medical care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Challenges of fracture risk assessment in Asian and Black women.The American journal of managed care · 2024
    Article
  3. Osteoporosis care amidst the prolonged pandemic.Journal of endocrinological investigation · 2021
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Peter Cram*Department of Medicine, University of Toronto †Division of General Internal Medicine and Geriatrics, Mt. Sinai/UHN Hospitals, Toronto, ON, Canada ‡Department of Internal Medicine, Division of General Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA §Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL Departments of ∥Biostatistics ¶Health Management and Policy, University of Iowa College of Public Health #University of Iowa College of Nursing **CADRE, Iowa City VA Healthcare System, Iowa City, IA ††Kaiser Permanente ‡‡School of Public Health, Georgia State University, Atlanta, GA §§Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL.
Kenneth G Saag
Yiyue Lou
Stephanie W Edmonds
Sylvie F Hall
Douglas W Roblin
Nicole C Wright
Michael P Jones
Fredric D Wolinsky
PAADRN Investigators*
Cancer Research And Biostatistics · USSinai Health System · CAUniversity of Alabama at Birmingham · USUniversity of Iowa · USIowa City VA Health Care System · US

Funding

A Patient Activation Intervention to Enhance Bone HealthR01AG033035 · NIA · UNIVERSITY OF IOWA · PI WOLINSKY, FREDRIC D · 2010 to 2014
$7.0M
UAB K12 in Patient Centered Outcomes ResearchK12HS023009 · AHRQ · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SAAG, KENNETH G · 2014 to 2018
$4.0M
Mid-Career Investigator Award (for Kenneth G. Saag, MD, MSc)K24AR052361 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SAAG, KENNETH G · 2005 to 2014
$1.7M
Building Musculoskeletal Outcomes Research at the University of IowaK24AR062133 · NIAMS · UNIVERSITY OF IOWA · PI CRAM, PETER M · 2012 to 2016
$594k
AHRQ HHS K12 HS023009NIAMS NIH HHS K24 AR052361NIAMS NIH HHS K24 AR062133NIA NIH HHS R01 AG033035
6 · The paper itself

Abstract

backgroundDetermining whether observed differences in health care can be called disparities requires persistence of differences after adjustment for relevant patient, provider, and health system factors. We examined whether providing dual-energy x-ray absorptiometry (DXA) test results directly to patients might reduce or eliminate racial differences in osteoporosis-related health care. DESIGN, SUBJECTS, AND MEASURES: We analyzed data from 3484 white and 1041 black women who underwent DXA testing at 2 health systems participating in the Patient Activation after DXA Result Notification (PAADRN) pragmatic clinical trial (ClinicalTrials.gov NCT-01507662) between February 2012 and August 2014. We examined 7 outcomes related to bone health at 12 weeks and 52 weeks post-DXA: (1) whether the patient correctly identified their DXA baseline results; (2) whether the patient was on guideline-concordant osteoporosis pharmacotherapy; (3) osteoporosis-related satisfaction; (4) osteoporosis knowledge; (5 and 6) osteoporosis self-efficacy for exercise and for diet; and (7) patient activation. We examined whether unadjusted differences in outcomes between whites and blacks persisted after adjusting for patient, provider, and health system factors.

resultsMean age was 66.5 years and 29% were black. At baseline black women had less education, poorer health status, and were less likely to report a history of osteoporosis (P<0.001 for all). In unadjusted analyses black women were less likely to correctly identify their actual DXA results, more likely to be on guideline-concordant therapy, and had similar patient activation. After adjustment for patient demographics, baseline health status and other factors, black women were still less likely to know their actual DXA result and less likely to be on guideline-concordant therapy, but black women had greater patient activation.

conclusionsAdjustment for patient and provider level factors can change how racial differences are viewed, unmasking new disparities, and providing explanations for others.

Indexed as

Black or African AmericanHealth Status DisparitiesWhite PeopleAgedFemaleHumansInterviews as TopicMaleModels, StatisticalOsteoporosisStatistics as Topic

Identifiers

PMID28288074
PMCPMC5432397
OpenAlexW2594041682

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.