Evidence map›Paper›PMID 28287074›Full record

ArticlePhysics in medicine and biology2017

Quantitative assessment of Cerenkov luminescence for radioguided brain tumor resection surgery.

Justin S Klein, Gregory S Mitchell, Simon R Cherry

Abstract read
In one paragraph

Article in Physics in medicine and biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Justin S KleinDepartment of Biomedical Engineering, University of California, Davis, CA, United States of America.
Gregory S MitchellDepartment of Biomedical Engineering, University of California, Davis, CA, United States of America.
Simon R CherryDepartment of Biomedical Engineering, University of California, Davis, CA, United States of America.

Funding

Quantitative Evaluation of Cerenkov Luminescence for Imaging and TherapyR01EB015471 · NIBIB · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHERRY, SIMON R · 2012 to 2015
$1.3M
NIBIB NIH HHS R01 EB015471
6 · The paper itself

Abstract

Cerenkov luminescence imaging (CLI) is a developing imaging modality that detects radiolabeled molecules via visible light emitted during the radioactive decay process. We used a Monte Carlo based computer simulation to quantitatively investigate CLI compared to direct detection of the ionizing radiation itself as an intraoperative imaging tool for assessment of brain tumor margins. Our brain tumor model consisted of a 1 mm spherical tumor remnant embedded up to 5 mm in depth below the surface of normal brain tissue. Tumor to background contrast ranging from 2:1 to 10:1 were considered. We quantified all decay signals (e

Indexed as

LuminescenceMonte Carlo MethodBrain NeoplasmsHumansModels, BiologicalPhotonsSurgery, Computer-Assisted

Identifiers

PMID28287074
PMCPMC5754015

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.