Evidence map›Paper›PMID 28287035›Full record

ReviewInternational journal of radiation biology2017

Biological basis of radiation protection needs rejuvenation.

Tatjana Paunesku, Benjamin Haley, Antone Brooks, Gayle E Woloschak

Abstract readReview
In one paragraph

Review in International journal of radiation biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. It Is Time to Move Beyond the Linear No-Threshold Theory for Low-Dose Radiation Protection.Dose-response : a publication of International Hormesis Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tatjana Pauneskua Department of Radiation Oncology , Northwestern University , Chicago , IL , USA.
Benjamin Haleya Department of Radiation Oncology , Northwestern University , Chicago , IL , USA.
Antone Brooksa Department of Radiation Oncology , Northwestern University , Chicago , IL , USA.
Gayle E Woloschaka Department of Radiation Oncology , Northwestern University , Chicago , IL , USA.

Funding

Radiation induced cancer risk reduction as a function of dose protraction: interspecies comparisonR01CA221150 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI WOLOSCHAK, GAYLE E. · 2017 to 2021
$1.7M
NCI NIH HHS R01 CA221150
6 · The paper itself

Abstract

purposeHuman beings encounter radiation in many different situations - from proximity to radioactive waste sites to participation in medical procedures using X-rays etc. Limits for radiation exposures are legally regulated; however, current radiation protection policy does not explicitly acknowledge that biological, cellular and molecular effects of low doses and low dose rates of radiation differ from effects induced by medium and high dose radiation exposures. Recent technical developments in biology and medicine, from single cell techniques to big data computational research, have enabled new approaches for study of biology of low doses of radiation. Results of the work done so far support the idea that low doses of radiation have effects that differ from those associated with high dose exposures; this work, however, is far from sufficient for the development of a new theoretical framework needed for the understanding of low dose radiation exposures.

conclusionsMechanistic understanding of radiation effects at low doses is necessary in order to develop better radiation protection policy.

Indexed as

Radiation ProtectionAnimalsDose-Response Relationship, RadiationHumansNeoplasms, Radiation-InducedPolicyRadiation ExposureRadiobiologyBiological effects of ionizing radiationlow dose radiationradiation protection

Identifiers

PMID28287035
PMCPMC7340141

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.